LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 5 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 2. - Dataset (ID:20313)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 82.50 | 19.50 | 7516 | 6031 | 1.2380 | 0.9833 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 80.50 | 19.50 | 7408 | 6018 | 1.2218 | 0.9817 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 76.60 | 19.50 | 7096 | 5898 | 1.1929 | 0.9801 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 78.50 | 19.50 | 7264 | 5949 | 1.2104 | 0.9774 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 84.40 | 19.50 | 7522 | 6038 | 1.2402 | 0.9766 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 74.60 | 19.50 | 6867 | 5927 | 1.1456 | 0.9739 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.1 | 22.40 | 19.50 | 1316 | 1150 | 1.1400 | 0.9727 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.1 | 24.30 | 19.50 | 1501 | 1322 | 1.1387 | 0.9726 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.1 | 20.40 | 19.50 | 1124 | 951 | 1.1748 | 0.9704 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 72.60 | 19.50 | 6672 | 5854 | 1.1260 | 0.9661 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 70.70 | 19.50 | 6447 | 5784 | 1.0983 | 0.9643 |
| MCF 10A-H2B-mCherry | Neratinib | 0.01 | 62.80 | 19.50 | 5707 | 5586 | 1.0274 | 0.9619 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.1 | 28.30 | 19.50 | 1801 | 1665 | 1.0832 | 0.9616 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 78.50 | 19.50 | 7201 | 5949 | 1.2107 | 0.9607 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.31623 | 76.60 | 19.50 | 6262 | 5898 | 1.0583 | 0.9605 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.1 | 26.30 | 19.50 | 1640 | 1491 | 1.1026 | 0.9605 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 76.60 | 19.50 | 7044 | 5898 | 1.1943 | 0.9599 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.31623 | 68.70 | 19.50 | 5670 | 5743 | 0.9847 | 0.9580 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 82.50 | 19.50 | 7318 | 6031 | 1.2143 | 0.9579 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 68.70 | 19.50 | 6204 | 5743 | 1.0628 | 0.9574 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 80.50 | 19.50 | 7279 | 6018 | 1.2099 | 0.9572 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.31623 | 78.50 | 19.50 | 6382 | 5949 | 1.0692 | 0.9565 |
| MCF 10A-H2B-mCherry | Etoposide | 0.56234 | 22.40 | 19.50 | 1029 | 1150 | 0.8918 | 0.9557 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 86.40 | 19.50 | 7403 | 6081 | 1.2138 | 0.9549 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.31623 | 72.60 | 19.50 | 5949 | 5854 | 1.0122 | 0.9534 |