LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 5 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 2. - Dataset (ID:20313)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | 0 | 94.30 | 19.50 | 6465 | 6154 | 1.0505 | 0.5767 | |
| MCF 10A-H2B-mCherry | Dasatinib | 0.01 | 94.30 | 19.50 | 5535 | 6154 | 0.8994 | 0.4815 |
| MCF 10A-H2B-mCherry | Etoposide | 3.1623 | 94.30 | 19.50 | 373 | 6154 | 0.0606 | 0.1644 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.31623 | 94.30 | 19.50 | 3345 | 6154 | 0.5429 | 0.7687 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 94.30 | 19.50 | 5947 | 6154 | 0.9673 | 0.6644 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.1 | 94.30 | 19.50 | 6333 | 6154 | 1.0295 | 0.6339 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.56234 | 94.30 | 19.50 | 6023 | 6154 | 0.9792 | 0.6129 |
| MCF 10A-H2B-mCherry | Taxol | 0.031623 | 94.30 | 19.50 | 21 | 6154 | 0.0035 | -0.1652 |
| MCF 10A-H2B-mCherry | Taxol | 0.01 | 94.30 | 19.50 | 6 | 6154 | 0.0010 | -0.2353 |
| MCF 10A-H2B-mCherry | Palbociclib | 10 | 94.30 | 19.50 | 626 | 6154 | 0.1016 | 0.3605 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.01 | 94.30 | 19.50 | 6264 | 6154 | 1.0178 | 0.5583 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.056667 | 94.30 | 19.50 | 5004 | 6154 | 0.8127 | 0.5854 |
| MCF 10A-H2B-mCherry | Etoposide | 0.0010833 | 94.30 | 19.50 | 6760 | 6154 | 1.0994 | 0.6088 |
| MCF 10A-H2B-mCherry | Etoposide | 0.31623 | 94.30 | 19.50 | 3075 | 6154 | 0.4996 | 0.5445 |
| MCF 10A-H2B-mCherry | Taxol | 0.31623 | 94.30 | 19.50 | 1 | 6154 | 0.0002 | -0.2925 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 94.30 | 19.50 | 7074 | 6154 | 1.1499 | 0.6009 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 94.30 | 19.50 | 1198 | 6154 | 0.1944 | 0.6372 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 94.30 | 19.50 | 3160 | 6154 | 0.5140 | 0.7356 |
| MCF 10A-H2B-mCherry | Neratinib | 0.1 | 94.30 | 19.50 | 5687 | 6154 | 0.9254 | 0.8974 |
| MCF 10A-H2B-mCherry | Palbociclib | 3.1623 | 94.30 | 19.50 | 1780 | 6154 | 0.2894 | 0.6483 |
| MCF 10A-H2B-mCherry | Taxol | 0.0002 | 94.30 | 19.50 | 6380 | 6154 | 1.0367 | 0.4923 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.1 | 94.30 | 19.50 | 6924 | 6154 | 1.1261 | 0.7152 |
| MCF 10A-H2B-mCherry | Etoposide | 0.056667 | 94.30 | 19.50 | 6051 | 6154 | 0.9845 | 0.4922 |
| MCF 10A-H2B-mCherry | Trametinib | 0.031623 | 94.30 | 19.50 | 1206 | 6154 | 0.1957 | 0.6117 |
| MCF 10A-H2B-mCherry | Alpelisib | 5.6234 | 94.30 | 19.50 | 5114 | 6154 | 0.8315 | 0.6283 |