LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 5 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 2. - Dataset (ID:20313)
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Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|
MCF 10A-H2B-mCherry | Alpelisib | 1.7783 | 10.60 | 19.50 | 500 | 467 | 1.0702 | 0.5317 |
MCF 10A-H2B-mCherry | Taxol | 0.0056234 | 10.60 | 19.50 | 535 | 467 | 1.1444 | 0.4657 |
MCF 10A-H2B-mCherry | Dasatinib | 3.1623 | 10.60 | 19.50 | 389 | 467 | 0.8344 | 0.5120 |
MCF 10A-H2B-mCherry | Palbociclib | 5.6234 | 10.60 | 19.50 | 459 | 467 | 0.9834 | 0.5387 |
MCF 10A-H2B-mCherry | Etoposide | 1 | 10.60 | 19.50 | 489 | 467 | 1.0483 | 0.6569 |
MCF 10A-H2B-mCherry | Neratinib | 0.0033333 | 10.60 | 19.50 | 451 | 467 | 0.9662 | 0.4699 |
MCF 10A-H2B-mCherry | Palbociclib | 3.1623 | 10.60 | 19.50 | 483 | 467 | 1.0337 | 0.5640 |
MCF 10A-H2B-mCherry | Palbociclib | 0.031667 | 10.60 | 19.50 | 485 | 467 | 1.0367 | 0.5317 |
MCF 10A-H2B-mCherry | Dasatinib | 0.56234 | 10.60 | 19.50 | 462 | 467 | 0.9896 | 0.4331 |
MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 10.60 | 19.50 | 490 | 467 | 1.0504 | 0.4989 |
MCF 10A-H2B-mCherry | Trametinib | 0.01 | 10.60 | 19.50 | 494 | 467 | 1.0580 | 0.5252 |
MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 10.60 | 19.50 | 451 | 467 | 0.9641 | 0.5243 |
MCF 10A-H2B-mCherry | Trametinib | 0.003 | 10.60 | 19.50 | 491 | 467 | 1.0502 | 0.5072 |
MCF 10A-H2B-mCherry | Dasatinib | 10 | 10.60 | 19.50 | 417 | 467 | 0.8929 | 0.4701 |
MCF 10A-H2B-mCherry | Neratinib | 0.56234 | 10.60 | 19.50 | 475 | 467 | 1.0170 | 0.4914 |
MCF 10A-H2B-mCherry | Alpelisib | 1 | 10.60 | 19.50 | 484 | 467 | 1.0384 | 0.5338 |
MCF 10A-H2B-mCherry | Taxol | 0.0018 | 10.60 | 19.50 | 535 | 467 | 1.1445 | 0.4943 |
MCF 10A-H2B-mCherry | Palbociclib | 0.01 | 10.60 | 19.50 | 540 | 467 | 1.1569 | 0.6131 |
MCF 10A-H2B-mCherry | Neratinib | 0.031623 | 10.60 | 19.50 | 446 | 467 | 0.9536 | 0.5637 |
MCF 10A-H2B-mCherry | Etoposide | 10 | 10.60 | 19.50 | 323 | 467 | 0.6917 | 0.3353 |
MCF 10A-H2B-mCherry | Dasatinib | 1.7783 | 10.60 | 19.50 | 435 | 467 | 0.9319 | 0.4161 |
MCF 10A-H2B-mCherry | Taxol | 0.0031623 | 10.60 | 19.50 | 518 | 467 | 1.1098 | 0.5334 |
MCF 10A-H2B-mCherry | Dasatinib | 0.0010833 | 10.60 | 19.50 | 517 | 467 | 1.1066 | 0.4893 |
MCF 10A-H2B-mCherry | Etoposide | 0.0010833 | 10.60 | 19.50 | 484 | 467 | 1.0365 | 0.5089 |
MCF 10A-H2B-mCherry | Etoposide | 0.056667 | 10.60 | 19.50 | 517 | 467 | 1.1068 | 0.5171 |