LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 5 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 2. - Dataset (ID:20313)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Etoposide | 10 | 14.50 | 19.50 | 337 | 537 | 0.6272 | 0.3347 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 32.20 | 19.50 | 337 | 2123 | 0.1592 | 0.1993 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 50.00 | 19.50 | 337 | 4744 | 0.0711 | 0.1796 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 4.60 | 19.50 | 337 | 295 | 1.1247 | 0.5044 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 22.40 | 19.50 | 337 | 1150 | 0.2942 | 0.2403 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 30.30 | 19.50 | 337 | 1887 | 0.1789 | 0.1933 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.17783 | 4.60 | 19.50 | 338 | 295 | 1.1588 | 0.5315 |
| MCF 10A-H2B-mCherry | Etoposide | 3.1623 | 14.50 | 19.50 | 338 | 537 | 0.6295 | 0.4159 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.031667 | 4.60 | 19.50 | 339 | 295 | 1.1572 | 0.4714 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.056667 | 4.60 | 19.50 | 339 | 295 | 1.1595 | 0.4690 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.01 | 4.60 | 19.50 | 340 | 295 | 1.1400 | 0.4656 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 59.80 | 19.50 | 340 | 5578 | 0.0624 | 0.1171 |
| MCF 10A-H2B-mCherry | Taxol | 0.01 | 20.40 | 19.50 | 340 | 951 | 0.3571 | 0.2807 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 20.40 | 19.50 | 341 | 951 | 0.3610 | 0.2585 |
| MCF 10A-H2B-mCherry | Etoposide | 0.56234 | 4.60 | 19.50 | 341 | 295 | 1.1764 | 0.5038 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 4.60 | 19.50 | 341 | 295 | 1.1488 | 0.4754 |
| MCF 10A-H2B-mCherry | Dasatinib | 10 | 4.60 | 19.50 | 341 | 295 | 1.1601 | 0.4697 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 44.00 | 19.50 | 341 | 3824 | 0.0895 | 0.1814 |
| MCF 10A-H2B-mCherry | Neratinib | 0.01 | 4.60 | 19.50 | 342 | 295 | 1.1659 | 0.4967 |
| MCF 10A-H2B-mCherry | Taxol | 0.0018 | 4.60 | 19.50 | 342 | 295 | 1.1616 | 0.4729 |
| MCF 10A-H2B-mCherry | Taxol | 0.00053333 | 4.60 | 19.50 | 344 | 295 | 1.1723 | 0.4759 |
| MCF 10A-H2B-mCherry | Vorinostat | 10 | 20.40 | 19.50 | 344 | 951 | 0.3644 | 0.3034 |
| MCF 10A-H2B-mCherry | Etoposide | 0.018333 | 4.60 | 19.50 | 345 | 295 | 1.1824 | 0.5689 |
| MCF 10A-H2B-mCherry | Taxol | 0.0056234 | 51.90 | 19.50 | 345 | 4974 | 0.0692 | 0.1190 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 4.60 | 19.50 | 345 | 295 | 1.1632 | 0.5416 |