LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 5 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 2. - Dataset (ID:20313)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Palbociclib | 0.17783 | 4.60 | 19.50 | 330 | 295 | 1.1128 | 0.4714 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 62.80 | 19.50 | 331 | 5586 | 0.0606 | 0.1146 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 24.30 | 19.50 | 331 | 1322 | 0.2508 | 0.2285 |
| MCF 10A-H2B-mCherry | Neratinib | 0.0053333 | 4.60 | 19.50 | 331 | 295 | 1.1305 | 0.4724 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 57.80 | 19.50 | 331 | 5483 | 0.0605 | 0.1468 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 51.90 | 19.50 | 332 | 4974 | 0.0666 | 0.1598 |
| MCF 10A-H2B-mCherry | Taxol | 0.0002 | 6.60 | 19.50 | 332 | 390 | 0.8493 | 0.3581 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 72.60 | 19.50 | 332 | 5854 | 0.0567 | 0.1613 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 18.40 | 19.50 | 333 | 775 | 0.4313 | 0.2749 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 34.20 | 19.50 | 333 | 2452 | 0.1363 | 0.1982 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 38.10 | 19.50 | 333 | 2867 | 0.1162 | 0.1772 |
| MCF 10A-H2B-mCherry | Vorinostat | 10 | 22.40 | 19.50 | 333 | 1150 | 0.2913 | 0.2861 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 36.20 | 19.50 | 334 | 2641 | 0.1269 | 0.1871 |
| MCF 10A-H2B-mCherry | 0 | 4.60 | 19.50 | 334 | 295 | 1.1360 | 0.4798 | |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 6.60 | 19.50 | 334 | 390 | 0.8545 | 0.4153 |
| MCF 10A-H2B-mCherry | Etoposide | 0.0010833 | 4.60 | 19.50 | 335 | 295 | 1.1253 | 0.4615 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 16.50 | 19.50 | 335 | 626 | 0.5369 | 0.2908 |
| MCF 10A-H2B-mCherry | Palbociclib | 10 | 6.60 | 19.50 | 335 | 390 | 0.8585 | 0.3952 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 42.10 | 19.50 | 335 | 3461 | 0.0970 | 0.1793 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.1 | 6.60 | 19.50 | 335 | 390 | 0.8587 | 0.4266 |
| MCF 10A-H2B-mCherry | Vorinostat | 5.6234 | 4.60 | 19.50 | 335 | 295 | 1.1470 | 0.5275 |
| MCF 10A-H2B-mCherry | Alpelisib | 10 | 4.60 | 19.50 | 335 | 295 | 1.1422 | 0.4748 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 46.00 | 19.50 | 336 | 4146 | 0.0812 | 0.1773 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 26.30 | 19.50 | 336 | 1491 | 0.2257 | 0.2011 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.31623 | 4.60 | 19.50 | 336 | 295 | 1.1230 | 0.4843 |