LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 5 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 2. - Dataset (ID:20313)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 2.70 | 19.50 | 211 | 163 | 1.2850 | 0.5969 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 2.70 | 19.50 | 211 | 163 | 1.2381 | 0.5116 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 2.70 | 19.50 | 212 | 163 | 1.3122 | 0.5947 |
| MCF 10A-H2B-mCherry | Etoposide | 0.31623 | 2.70 | 19.50 | 214 | 163 | 1.3287 | 0.6469 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 90.40 | 19.50 | 214 | 6097 | 0.0352 | 0.0184 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.031667 | 2.70 | 19.50 | 214 | 163 | 1.3164 | 0.6413 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.031667 | 2.70 | 19.50 | 215 | 163 | 1.3464 | 0.5860 |
| MCF 10A-H2B-mCherry | Taxol | 0.0031623 | 64.70 | 19.50 | 215 | 5643 | 0.0369 | 0.1106 |
| MCF 10A-H2B-mCherry | Taxol | 0.1 | 10.60 | 19.50 | 215 | 467 | 0.4623 | 0.3725 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 2.70 | 19.50 | 215 | 163 | 1.2932 | 0.5520 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 78.50 | 19.50 | 216 | 5949 | 0.0371 | 0.0499 |
| MCF 10A-H2B-mCherry | Vorinostat | 3.1623 | 2.70 | 19.50 | 216 | 163 | 1.3133 | 0.5932 |
| MCF 10A-H2B-mCherry | Alpelisib | 1.7783 | 2.70 | 19.50 | 217 | 163 | 1.3465 | 0.6269 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.01 | 2.70 | 19.50 | 217 | 163 | 1.3510 | 0.5622 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.31623 | 2.70 | 19.50 | 218 | 163 | 1.2814 | 0.5530 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.031667 | 2.70 | 19.50 | 218 | 163 | 1.2876 | 0.5827 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 88.40 | 19.50 | 219 | 6064 | 0.0362 | 0.0214 |
| MCF 10A-H2B-mCherry | Etoposide | 0.056667 | 2.70 | 19.50 | 219 | 163 | 1.3152 | 0.5655 |
| MCF 10A-H2B-mCherry | Etoposide | 0.1 | 2.70 | 19.50 | 220 | 163 | 1.3182 | 0.5554 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 76.60 | 19.50 | 220 | 5898 | 0.0381 | 0.0586 |
| MCF 10A-H2B-mCherry | Taxol | 0.017783 | 4.60 | 19.50 | 221 | 295 | 0.7472 | 0.3368 |
| MCF 10A-H2B-mCherry | Taxol | 0.0018 | 2.70 | 19.50 | 221 | 163 | 1.3478 | 0.5779 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 2.70 | 19.50 | 221 | 163 | 1.3192 | 0.5892 |
| MCF 10A-H2B-mCherry | Neratinib | 0.0053333 | 2.70 | 19.50 | 222 | 163 | 1.3866 | 0.6075 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 86.40 | 19.50 | 222 | 6081 | 0.0368 | 0.0279 |