LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 5 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 2. - Dataset (ID:20313)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Etoposide | 0.01 | 2.70 | 19.50 | 175 | 163 | 1.0585 | 0.4767 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.17783 | 2.70 | 19.50 | 176 | 163 | 1.0826 | 0.4857 |
| MCF 10A-H2B-mCherry | Palbociclib | 1.7783 | 2.70 | 19.50 | 177 | 163 | 1.0537 | 0.4236 |
| MCF 10A-H2B-mCherry | Taxol | 0.0056234 | 62.80 | 19.50 | 177 | 5586 | 0.0314 | 0.0366 |
| MCF 10A-H2B-mCherry | Taxol | 0.017783 | 2.70 | 19.50 | 178 | 163 | 1.0913 | 0.4696 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.31623 | 2.70 | 19.50 | 178 | 163 | 1.0931 | 0.4780 |
| MCF 10A-H2B-mCherry | Vorinostat | 1.7783 | 2.70 | 19.50 | 178 | 163 | 1.0804 | 0.5148 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.17783 | 2.70 | 19.50 | 181 | 163 | 1.1313 | 0.5233 |
| MCF 10A-H2B-mCherry | Taxol | 0.0031623 | 66.70 | 19.50 | 183 | 5728 | 0.0312 | 0.0841 |
| MCF 10A-H2B-mCherry | Taxol | 0.031623 | 20.40 | 19.50 | 184 | 951 | 0.1939 | 0.1925 |
| MCF 10A-H2B-mCherry | Taxol | 0.001 | 2.70 | 19.50 | 184 | 163 | 1.1240 | 0.5009 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.056667 | 2.70 | 19.50 | 185 | 163 | 1.0997 | 0.3561 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 2.70 | 19.50 | 186 | 163 | 1.1117 | 0.4786 |
| MCF 10A-H2B-mCherry | Etoposide | 0.0033333 | 2.70 | 19.50 | 188 | 163 | 1.1163 | 0.4682 |
| MCF 10A-H2B-mCherry | Taxol | 0.00033333 | 2.70 | 19.50 | 190 | 163 | 1.1373 | 0.5371 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.056667 | 2.70 | 19.50 | 191 | 163 | 1.1907 | 0.5247 |
| MCF 10A-H2B-mCherry | Taxol | 0.0031623 | 2.70 | 19.50 | 191 | 163 | 1.1577 | 0.5250 |
| MCF 10A-H2B-mCherry | Dasatinib | 1.7783 | 2.70 | 19.50 | 192 | 163 | 1.1654 | 0.4810 |
| MCF 10A-H2B-mCherry | Taxol | 0.01 | 30.30 | 19.50 | 192 | 1887 | 0.1021 | 0.0962 |
| MCF 10A-H2B-mCherry | Vorinostat | 5.6234 | 2.70 | 19.50 | 193 | 163 | 1.1897 | 0.5656 |
| MCF 10A-H2B-mCherry | Alpelisib | 3.1623 | 2.70 | 19.50 | 193 | 163 | 1.1667 | 0.4972 |
| MCF 10A-H2B-mCherry | Taxol | 0.00053333 | 2.70 | 19.50 | 193 | 163 | 1.2088 | 0.5162 |
| MCF 10A-H2B-mCherry | Neratinib | 0.0033333 | 2.70 | 19.50 | 197 | 163 | 1.1608 | 0.4880 |
| MCF 10A-H2B-mCherry | Neratinib | 0.018 | 2.70 | 19.50 | 197 | 163 | 1.1849 | 0.5401 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.031667 | 2.70 | 19.50 | 198 | 163 | 1.1980 | 0.5324 |