LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 5 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 2. - Dataset (ID:20313)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 10.60 | 19.50 | 402 | 467 | 0.8609 | 0.5405 |
| MCF 10A-H2B-mCherry | Alpelisib | 1 | 10.60 | 19.50 | 484 | 467 | 1.0384 | 0.5338 |
| MCF 10A-H2B-mCherry | Trametinib | 0.031623 | 10.60 | 19.50 | 441 | 467 | 0.9439 | 0.5210 |
| MCF 10A-H2B-mCherry | Etoposide | 3.1623 | 10.60 | 19.50 | 320 | 467 | 0.6857 | 0.3929 |
| MCF 10A-H2B-mCherry | Etoposide | 0.01 | 10.60 | 19.50 | 504 | 467 | 1.0788 | 0.6423 |
| MCF 10A-H2B-mCherry | Dasatinib | 3.1623 | 10.60 | 19.50 | 389 | 467 | 0.8344 | 0.5120 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.1 | 10.60 | 19.50 | 414 | 467 | 0.8878 | 0.4377 |
| MCF 10A-H2B-mCherry | Neratinib | 0.1 | 10.60 | 19.50 | 453 | 467 | 0.9694 | 0.4895 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 10.60 | 19.50 | 468 | 467 | 1.0008 | 0.5502 |
| MCF 10A-H2B-mCherry | Palbociclib | 10 | 10.60 | 19.50 | 416 | 467 | 0.8908 | 0.4589 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 10.60 | 19.50 | 451 | 467 | 0.9641 | 0.5243 |
| MCF 10A-H2B-mCherry | Dasatinib | 10 | 10.60 | 19.50 | 417 | 467 | 0.8929 | 0.4701 |
| MCF 10A-H2B-mCherry | Taxol | 0.0031623 | 10.60 | 19.50 | 518 | 467 | 1.1098 | 0.5334 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 10.60 | 19.50 | 494 | 467 | 1.0580 | 0.5252 |
| MCF 10A-H2B-mCherry | Etoposide | 0.56234 | 10.60 | 19.50 | 459 | 467 | 0.9806 | 0.6272 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.031667 | 10.60 | 19.50 | 472 | 467 | 1.0107 | 0.5463 |
| MCF 10A-H2B-mCherry | Taxol | 0.01 | 10.60 | 19.50 | 377 | 467 | 0.8071 | 0.4542 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.56234 | 10.60 | 19.50 | 504 | 467 | 1.0804 | 0.5284 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.31623 | 10.60 | 19.50 | 465 | 467 | 0.9958 | 0.4792 |
| MCF 10A-H2B-mCherry | Palbociclib | 5.6234 | 10.60 | 19.50 | 459 | 467 | 0.9834 | 0.5387 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.0033333 | 10.60 | 19.50 | 480 | 467 | 1.0277 | 0.4908 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.056667 | 10.60 | 19.50 | 452 | 467 | 0.9682 | 0.4976 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 10.60 | 19.50 | 430 | 467 | 0.9213 | 0.4720 |
| MCF 10A-H2B-mCherry | Etoposide | 0.0010833 | 10.60 | 19.50 | 484 | 467 | 1.0365 | 0.5089 |
| MCF 10A-H2B-mCherry | Vorinostat | 3.1623 | 10.60 | 19.50 | 402 | 467 | 0.8613 | 0.4165 |