LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 5 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 2. - Dataset (ID:20313)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | 0 | 6.60 | 19.50 | 422 | 390 | 1.0817 | 0.4677 | |
| MCF 10A-H2B-mCherry | Palbociclib | 10 | 6.60 | 19.50 | 335 | 390 | 0.8585 | 0.3952 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 6.60 | 19.50 | 425 | 390 | 1.0897 | 0.5436 |
| MCF 10A-H2B-mCherry | Alpelisib | 10 | 6.60 | 19.50 | 385 | 390 | 0.9870 | 0.4587 |
| MCF 10A-H2B-mCherry | Dasatinib | 1.7783 | 6.60 | 19.50 | 369 | 390 | 0.9442 | 0.4024 |
| MCF 10A-H2B-mCherry | Palbociclib | 1 | 6.60 | 19.50 | 425 | 390 | 1.0879 | 0.4476 |
| MCF 10A-H2B-mCherry | Taxol | 0.31623 | 6.60 | 19.50 | 247 | 390 | 0.6340 | 0.3424 |
| MCF 10A-H2B-mCherry | Taxol | 0.1 | 6.60 | 19.50 | 230 | 390 | 0.5891 | 0.3086 |
| MCF 10A-H2B-mCherry | Neratinib | 0.0053333 | 6.60 | 19.50 | 405 | 390 | 1.0384 | 0.4518 |
| MCF 10A-H2B-mCherry | Etoposide | 3.1623 | 6.60 | 19.50 | 269 | 390 | 0.6890 | 0.3304 |
| MCF 10A-H2B-mCherry | Neratinib | 0.01 | 6.60 | 19.50 | 404 | 390 | 1.0340 | 0.4442 |
| MCF 10A-H2B-mCherry | Taxol | 0.031623 | 6.60 | 19.50 | 290 | 390 | 0.7422 | 0.4383 |
| MCF 10A-H2B-mCherry | Etoposide | 0.031667 | 6.60 | 19.50 | 432 | 390 | 1.1074 | 0.4496 |
| MCF 10A-H2B-mCherry | Neratinib | 0.56234 | 6.60 | 19.50 | 448 | 390 | 1.1472 | 0.5195 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.031667 | 6.60 | 19.50 | 408 | 390 | 1.0458 | 0.5061 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.56234 | 6.60 | 19.50 | 384 | 390 | 0.9833 | 0.4208 |
| MCF 10A-H2B-mCherry | Palbociclib | 1.7783 | 6.60 | 19.50 | 399 | 390 | 1.0233 | 0.4284 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.56234 | 6.60 | 19.50 | 425 | 390 | 1.0874 | 0.5014 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.31623 | 6.60 | 19.50 | 405 | 390 | 1.0379 | 0.4356 |
| MCF 10A-H2B-mCherry | Etoposide | 0.0033333 | 6.60 | 19.50 | 367 | 390 | 0.9406 | 0.4059 |
| MCF 10A-H2B-mCherry | Taxol | 0.017783 | 6.60 | 19.50 | 239 | 390 | 0.6129 | 0.3082 |
| MCF 10A-H2B-mCherry | Dasatinib | 10 | 6.60 | 19.50 | 382 | 390 | 0.9776 | 0.4502 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.17783 | 6.60 | 19.50 | 405 | 390 | 1.0380 | 0.4637 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.31623 | 6.60 | 19.50 | 413 | 390 | 1.0585 | 0.4585 |
| MCF 10A-H2B-mCherry | Taxol | 0.01 | 6.60 | 19.50 | 267 | 390 | 0.6850 | 0.3359 |