LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 5 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 2. - Dataset (ID:20313)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Taxol | 0.001 | 46.00 | 19.50 | 1883 | 4146 | 0.4543 | 0.5966 |
| MCF 10A-H2B-mCherry | Taxol | 0.001 | 59.80 | 19.50 | 2609 | 5578 | 0.4805 | 0.4377 |
| MCF 10A-H2B-mCherry | Taxol | 0.001 | 30.30 | 19.50 | 1269 | 1887 | 0.6727 | 0.6870 |
| MCF 10A-H2B-mCherry | Taxol | 0.001 | 28.30 | 19.50 | 1184 | 1665 | 0.7125 | 0.6706 |
| MCF 10A-H2B-mCherry | Taxol | 0.001 | 32.20 | 19.50 | 1392 | 2123 | 0.6550 | 0.6686 |
| MCF 10A-H2B-mCherry | Taxol | 0.001 | 24.30 | 19.50 | 1059 | 1322 | 0.8052 | 0.6911 |
| MCF 10A-H2B-mCherry | Taxol | 0.001 | 26.30 | 19.50 | 1120 | 1491 | 0.7536 | 0.6758 |
| MCF 10A-H2B-mCherry | Taxol | 0.001 | 34.20 | 19.50 | 1486 | 2452 | 0.6026 | 0.6418 |
| MCF 10A-H2B-mCherry | Taxol | 0.001 | 22.40 | 19.50 | 960 | 1150 | 0.8281 | 0.6675 |
| MCF 10A-H2B-mCherry | Taxol | 0.001 | 36.20 | 19.50 | 1530 | 2641 | 0.5775 | 0.6099 |
| MCF 10A-H2B-mCherry | Taxol | 0.001 | 62.80 | 19.50 | 2751 | 5586 | 0.5047 | 0.4407 |
| MCF 10A-H2B-mCherry | Taxol | 0.001 | 14.50 | 19.50 | 565 | 537 | 1.0518 | 0.5964 |
| MCF 10A-H2B-mCherry | Taxol | 0.001 | 16.50 | 19.50 | 629 | 626 | 1.0003 | 0.5878 |
| MCF 10A-H2B-mCherry | Taxol | 0.001 | 18.40 | 19.50 | 730 | 775 | 0.9366 | 0.6052 |
| MCF 10A-H2B-mCherry | Taxol | 0.001 | 20.40 | 19.50 | 846 | 951 | 0.8805 | 0.6384 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 8.60 | 19.50 | 469 | 442 | 1.0606 | 0.5540 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 6.60 | 19.50 | 425 | 390 | 1.0897 | 0.5436 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 4.60 | 19.50 | 345 | 295 | 1.1632 | 0.5416 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 2.70 | 19.50 | 234 | 163 | 1.4322 | 0.6589 |
| MCF 10A-H2B-mCherry | Taxol | 0.001 | 8.60 | 19.50 | 456 | 442 | 1.0308 | 0.5080 |
| MCF 10A-H2B-mCherry | Taxol | 0.001 | 6.60 | 19.50 | 387 | 390 | 0.9923 | 0.4456 |
| MCF 10A-H2B-mCherry | Taxol | 0.001 | 4.60 | 19.50 | 306 | 295 | 1.0446 | 0.4375 |
| MCF 10A-H2B-mCherry | Taxol | 0.001 | 2.70 | 19.50 | 184 | 163 | 1.1240 | 0.5009 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 16.50 | 19.50 | 626 | 626 | 1.0018 | 0.5550 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 14.50 | 19.50 | 561 | 537 | 1.0449 | 0.5594 |