LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 5 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 2. - Dataset (ID:20313)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Taxol | 0.00033333 | 38.10 | 19.50 | 2523 | 2867 | 0.8834 | 0.8665 |
| MCF 10A-H2B-mCherry | Taxol | 0.00033333 | 40.10 | 19.50 | 2729 | 3104 | 0.8805 | 0.8627 |
| MCF 10A-H2B-mCherry | Taxol | 0.00033333 | 70.70 | 19.50 | 5287 | 5784 | 0.9152 | 0.6960 |
| MCF 10A-H2B-mCherry | Taxol | 0.00033333 | 72.60 | 19.50 | 5460 | 5854 | 0.9333 | 0.7581 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 32.20 | 19.50 | 1863 | 2123 | 0.8794 | 0.7998 |
| MCF 10A-H2B-mCherry | Taxol | 0.00033333 | 14.50 | 19.50 | 569 | 537 | 1.0587 | 0.5993 |
| MCF 10A-H2B-mCherry | Taxol | 0.00033333 | 16.50 | 19.50 | 624 | 626 | 0.9993 | 0.6198 |
| MCF 10A-H2B-mCherry | Taxol | 0.00033333 | 12.50 | 19.50 | 523 | 495 | 1.0558 | 0.5602 |
| MCF 10A-H2B-mCherry | Taxol | 0.00033333 | 18.40 | 19.50 | 734 | 775 | 0.9501 | 0.6774 |
| MCF 10A-H2B-mCherry | Taxol | 0.00033333 | 8.60 | 19.50 | 454 | 442 | 1.0266 | 0.5100 |
| MCF 10A-H2B-mCherry | Taxol | 0.00033333 | 10.60 | 19.50 | 496 | 467 | 1.0622 | 0.5898 |
| MCF 10A-H2B-mCherry | Taxol | 0.00033333 | 20.40 | 19.50 | 877 | 951 | 0.9310 | 0.7561 |
| MCF 10A-H2B-mCherry | Taxol | 0.00033333 | 4.60 | 19.50 | 316 | 295 | 1.0614 | 0.5041 |
| MCF 10A-H2B-mCherry | Taxol | 0.00033333 | 6.60 | 19.50 | 389 | 390 | 0.9968 | 0.4853 |
| MCF 10A-H2B-mCherry | Taxol | 0.00033333 | 22.40 | 19.50 | 1054 | 1150 | 0.9242 | 0.7671 |
| MCF 10A-H2B-mCherry | Taxol | 0.00033333 | 24.30 | 19.50 | 1251 | 1322 | 0.9405 | 0.7688 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 12.50 | 19.50 | 538 | 495 | 1.0869 | 0.6210 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 10.60 | 19.50 | 500 | 467 | 1.0709 | 0.5382 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 8.60 | 19.50 | 469 | 442 | 1.0613 | 0.5140 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 6.60 | 19.50 | 418 | 390 | 1.0715 | 0.5187 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 4.60 | 19.50 | 337 | 295 | 1.1247 | 0.5044 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 2.70 | 19.50 | 221 | 163 | 1.3192 | 0.5892 |
| MCF 10A-H2B-mCherry | Taxol | 0.00033333 | 26.30 | 19.50 | 1370 | 1491 | 0.9155 | 0.7637 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 36.20 | 19.50 | 2350 | 2641 | 0.8950 | 0.7761 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 34.20 | 19.50 | 2102 | 2452 | 0.8666 | 0.7860 |