LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 5 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 2. - Dataset (ID:20313)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Etoposide | 1.7783 | 62.80 | 19.50 | 612 | 5586 | 0.1095 | 0.4030 |
| MCF 10A-H2B-mCherry | Vorinostat | 3.1623 | 42.10 | 19.50 | 380 | 3461 | 0.1098 | 0.2139 |
| MCF 10A-H2B-mCherry | Neratinib | 0.56234 | 66.70 | 19.50 | 622 | 5728 | 0.1098 | 0.4168 |
| MCF 10A-H2B-mCherry | Palbociclib | 10 | 68.70 | 19.50 | 624 | 5743 | 0.1103 | 0.4253 |
| MCF 10A-H2B-mCherry | Etoposide | 1.7783 | 59.80 | 19.50 | 617 | 5578 | 0.1104 | 0.4128 |
| MCF 10A-H2B-mCherry | Vorinostat | 5.6234 | 42.10 | 19.50 | 383 | 3461 | 0.1106 | 0.2856 |
| MCF 10A-H2B-mCherry | Neratinib | 0.56234 | 57.80 | 19.50 | 601 | 5483 | 0.1106 | 0.4009 |
| MCF 10A-H2B-mCherry | Taxol | 0.0056234 | 48.00 | 19.50 | 493 | 4441 | 0.1112 | 0.1678 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 50.00 | 19.50 | 529 | 4744 | 0.1113 | 0.3163 |
| MCF 10A-H2B-mCherry | Palbociclib | 10 | 53.90 | 19.50 | 577 | 5154 | 0.1123 | 0.4145 |
| MCF 10A-H2B-mCherry | Palbociclib | 10 | 51.90 | 19.50 | 559 | 4974 | 0.1125 | 0.3738 |
| MCF 10A-H2B-mCherry | Neratinib | 0.56234 | 62.80 | 19.50 | 624 | 5586 | 0.1129 | 0.4129 |
| MCF 10A-H2B-mCherry | Taxol | 0.0018 | 74.60 | 19.50 | 665 | 5927 | 0.1138 | 0.1846 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 38.10 | 19.50 | 333 | 2867 | 0.1162 | 0.1772 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 42.10 | 19.50 | 402 | 3461 | 0.1163 | 0.2094 |
| MCF 10A-H2B-mCherry | Dasatinib | 10 | 44.00 | 19.50 | 445 | 3824 | 0.1164 | 0.3729 |
| MCF 10A-H2B-mCherry | Palbociclib | 10 | 50.00 | 19.50 | 553 | 4744 | 0.1166 | 0.3784 |
| MCF 10A-H2B-mCherry | Vorinostat | 10 | 34.20 | 19.50 | 285 | 2452 | 0.1167 | 0.1669 |
| MCF 10A-H2B-mCherry | Neratinib | 0.56234 | 53.90 | 19.50 | 601 | 5154 | 0.1171 | 0.4167 |
| MCF 10A-H2B-mCherry | Taxol | 0.0056234 | 46.00 | 19.50 | 487 | 4146 | 0.1176 | 0.1697 |
| MCF 10A-H2B-mCherry | Etoposide | 1.7783 | 57.80 | 19.50 | 647 | 5483 | 0.1176 | 0.4255 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 48.00 | 19.50 | 525 | 4441 | 0.1180 | 0.3158 |
| MCF 10A-H2B-mCherry | Etoposide | 3.1623 | 46.00 | 19.50 | 490 | 4146 | 0.1182 | 0.3983 |
| MCF 10A-H2B-mCherry | Neratinib | 0.56234 | 51.90 | 19.50 | 602 | 4974 | 0.1214 | 0.4267 |
| MCF 10A-H2B-mCherry | Etoposide | 1.7783 | 55.90 | 19.50 | 655 | 5348 | 0.1219 | 0.4339 |