LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 5 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 2. - Dataset (ID:20313)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | 0 | 4.60 | 19.50 | 334 | 295 | 1.1360 | 0.4798 | |
| MCF 10A-H2B-mCherry | Alpelisib | 0.0033333 | 12.50 | 19.50 | 563 | 495 | 1.1366 | 0.6069 |
| MCF 10A-H2B-mCherry | Taxol | 0.00013333 | 14.50 | 19.50 | 611 | 537 | 1.1368 | 0.5762 |
| MCF 10A-H2B-mCherry | Taxol | 0.00013333 | 12.50 | 19.50 | 563 | 495 | 1.1373 | 0.5246 |
| MCF 10A-H2B-mCherry | Taxol | 0.00033333 | 2.70 | 19.50 | 190 | 163 | 1.1373 | 0.5371 |
| MCF 10A-H2B-mCherry | Taxol | 0.00053333 | 8.60 | 19.50 | 503 | 442 | 1.1378 | 0.4580 |
| MCF 10A-H2B-mCherry | Etoposide | 0.01 | 20.40 | 19.50 | 1062 | 951 | 1.1379 | 0.8873 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.1 | 24.30 | 19.50 | 1501 | 1322 | 1.1387 | 0.9726 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.1 | 12.50 | 19.50 | 564 | 495 | 1.1391 | 0.6870 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.0033333 | 8.60 | 19.50 | 504 | 442 | 1.1391 | 0.6178 |
| MCF 10A-H2B-mCherry | Alpelisib | 5.6234 | 6.60 | 19.50 | 445 | 390 | 1.1393 | 0.4887 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.01 | 4.60 | 19.50 | 340 | 295 | 1.1400 | 0.4656 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.1 | 22.40 | 19.50 | 1316 | 1150 | 1.1400 | 0.9727 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 10.60 | 19.50 | 533 | 467 | 1.1414 | 0.5181 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.0033333 | 10.60 | 19.50 | 533 | 467 | 1.1414 | 0.6560 |
| MCF 10A-H2B-mCherry | Alpelisib | 10 | 4.60 | 19.50 | 335 | 295 | 1.1422 | 0.4748 |
| MCF 10A-H2B-mCherry | Taxol | 0.0018 | 12.50 | 19.50 | 566 | 495 | 1.1423 | 0.4857 |
| MCF 10A-H2B-mCherry | Neratinib | 0.0053333 | 94.30 | 19.50 | 7025 | 6154 | 1.1423 | 0.6590 |
| MCF 10A-H2B-mCherry | Etoposide | 0.1 | 14.50 | 19.50 | 614 | 537 | 1.1429 | 0.7105 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.0033333 | 8.60 | 19.50 | 506 | 442 | 1.1433 | 0.5776 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 6.60 | 19.50 | 447 | 390 | 1.1437 | 0.4737 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.01 | 12.50 | 19.50 | 567 | 495 | 1.1438 | 0.6260 |
| MCF 10A-H2B-mCherry | Taxol | 0.00053333 | 10.60 | 19.50 | 535 | 467 | 1.1440 | 0.4590 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 59.80 | 19.50 | 6566 | 5578 | 1.1444 | 0.8751 |
| MCF 10A-H2B-mCherry | Taxol | 0.0056234 | 10.60 | 19.50 | 535 | 467 | 1.1444 | 0.4657 |