LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 5 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 2. - Dataset (ID:20313)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Vorinostat | 10 | 57.80 | 19.50 | 265 | 5483 | 0.0486 | 0.1223 |
| MCF 10A-H2B-mCherry | Vorinostat | 10 | 55.90 | 19.50 | 262 | 5348 | 0.0491 | 0.1221 |
| MCF 10A-H2B-mCherry | Dasatinib | 10 | 82.50 | 19.50 | 304 | 6031 | 0.0504 | 0.1574 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 68.70 | 19.50 | 284 | 5743 | 0.0507 | 0.1002 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 86.40 | 19.50 | 309 | 6081 | 0.0508 | 0.1579 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 94.30 | 19.50 | 312 | 6154 | 0.0508 | 0.1215 |
| MCF 10A-H2B-mCherry | Dasatinib | 10 | 80.50 | 19.50 | 307 | 6018 | 0.0510 | 0.1721 |
| MCF 10A-H2B-mCherry | Vorinostat | 10 | 53.90 | 19.50 | 265 | 5154 | 0.0515 | 0.1098 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 92.30 | 19.50 | 318 | 6153 | 0.0517 | 0.1389 |
| MCF 10A-H2B-mCherry | Taxol | 0.0056234 | 53.90 | 19.50 | 268 | 5154 | 0.0517 | 0.0945 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 90.40 | 19.50 | 317 | 6097 | 0.0521 | 0.1394 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 88.40 | 19.50 | 318 | 6064 | 0.0524 | 0.1480 |
| MCF 10A-H2B-mCherry | Taxol | 0.0031623 | 57.80 | 19.50 | 297 | 5483 | 0.0526 | 0.1404 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 66.70 | 19.50 | 295 | 5728 | 0.0526 | 0.1035 |
| MCF 10A-H2B-mCherry | Vorinostat | 10 | 51.90 | 19.50 | 262 | 4974 | 0.0527 | 0.1152 |
| MCF 10A-H2B-mCherry | Taxol | 0.0018 | 94.30 | 19.50 | 325 | 6154 | 0.0528 | 0.1060 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 82.50 | 19.50 | 320 | 6031 | 0.0531 | 0.1686 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 80.50 | 19.50 | 319 | 6018 | 0.0531 | 0.1524 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 84.40 | 19.50 | 322 | 6038 | 0.0533 | 0.1678 |
| MCF 10A-H2B-mCherry | Vorinostat | 10 | 50.00 | 19.50 | 253 | 4744 | 0.0534 | 0.1160 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 78.50 | 19.50 | 320 | 5949 | 0.0539 | 0.1514 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 76.60 | 19.50 | 322 | 5898 | 0.0546 | 0.1569 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 74.60 | 19.50 | 325 | 5927 | 0.0549 | 0.1617 |
| MCF 10A-H2B-mCherry | Taxol | 0.1 | 20.40 | 19.50 | 51 | 951 | 0.0551 | -0.0789 |
| MCF 10A-H2B-mCherry | Dasatinib | 10 | 78.50 | 19.50 | 329 | 5949 | 0.0554 | 0.1834 |