LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 5 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 2. - Dataset (ID:20313)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Dasatinib | 3.1623 | 40.10 | 19.50 | 672 | 3104 | 0.2169 | 0.3981 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.56234 | 8.60 | 19.50 | 398 | 442 | 0.9021 | 0.3981 |
| MCF 10A-H2B-mCherry | Etoposide | 3.1623 | 46.00 | 19.50 | 490 | 4146 | 0.1182 | 0.3983 |
| MCF 10A-H2B-mCherry | Neratinib | 0.56234 | 78.50 | 19.50 | 615 | 5949 | 0.1036 | 0.3984 |
| MCF 10A-H2B-mCherry | Neratinib | 0.0053333 | 20.40 | 19.50 | 704 | 951 | 0.7407 | 0.3984 |
| MCF 10A-H2B-mCherry | Palbociclib | 10 | 82.50 | 19.50 | 613 | 6031 | 0.1020 | 0.3986 |
| MCF 10A-H2B-mCherry | Palbociclib | 1.7783 | 4.60 | 19.50 | 291 | 295 | 0.9744 | 0.3990 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 4.60 | 19.50 | 275 | 295 | 0.9206 | 0.3990 |
| MCF 10A-H2B-mCherry | Palbociclib | 10 | 76.60 | 19.50 | 626 | 5898 | 0.1068 | 0.3992 |
| MCF 10A-H2B-mCherry | Dasatinib | 3.1623 | 28.30 | 19.50 | 524 | 1665 | 0.3144 | 0.3996 |
| MCF 10A-H2B-mCherry | Vorinostat | 3.1623 | 14.50 | 19.50 | 394 | 537 | 0.7340 | 0.3996 |
| MCF 10A-H2B-mCherry | Taxol | 0.0031623 | 26.30 | 19.50 | 783 | 1491 | 0.5255 | 0.3999 |
| MCF 10A-H2B-mCherry | Neratinib | 0.56234 | 68.70 | 19.50 | 599 | 5743 | 0.1053 | 0.4000 |
| MCF 10A-H2B-mCherry | Neratinib | 0.56234 | 57.80 | 19.50 | 601 | 5483 | 0.1106 | 0.4009 |
| MCF 10A-H2B-mCherry | Dasatinib | 1.7783 | 12.50 | 19.50 | 451 | 495 | 0.9099 | 0.4010 |
| MCF 10A-H2B-mCherry | Dasatinib | 1.7783 | 14.50 | 19.50 | 467 | 537 | 0.8686 | 0.4012 |
| MCF 10A-H2B-mCherry | Neratinib | 0.56234 | 59.80 | 19.50 | 603 | 5578 | 0.1089 | 0.4013 |
| MCF 10A-H2B-mCherry | Dasatinib | 10 | 38.10 | 19.50 | 449 | 2867 | 0.1567 | 0.4015 |
| MCF 10A-H2B-mCherry | Neratinib | 0.0053333 | 22.40 | 19.50 | 768 | 1150 | 0.6684 | 0.4016 |
| MCF 10A-H2B-mCherry | Palbociclib | 10 | 62.80 | 19.50 | 591 | 5586 | 0.1071 | 0.4020 |
| MCF 10A-H2B-mCherry | Vorinostat | 1.7783 | 36.20 | 19.50 | 623 | 2641 | 0.2365 | 0.4022 |
| MCF 10A-H2B-mCherry | Palbociclib | 1 | 48.00 | 19.50 | 888 | 4441 | 0.2000 | 0.4022 |
| MCF 10A-H2B-mCherry | Dasatinib | 1.7783 | 6.60 | 19.50 | 369 | 390 | 0.9442 | 0.4024 |
| MCF 10A-H2B-mCherry | Palbociclib | 10 | 80.50 | 19.50 | 610 | 6018 | 0.1019 | 0.4029 |
| MCF 10A-H2B-mCherry | Etoposide | 1.7783 | 62.80 | 19.50 | 612 | 5586 | 0.1095 | 0.4030 |