LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 5 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 2. - Dataset (ID:20313)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Etoposide | 10 | 16.50 | 19.50 | 335 | 626 | 0.5369 | 0.2908 |
| MCF 10A-H2B-mCherry | Vorinostat | 5.6234 | 40.10 | 19.50 | 383 | 3104 | 0.1233 | 0.2913 |
| MCF 10A-H2B-mCherry | Vorinostat | 5.6234 | 88.40 | 19.50 | 374 | 6064 | 0.0618 | 0.2920 |
| MCF 10A-H2B-mCherry | Taxol | 0.31623 | 10.60 | 19.50 | 227 | 467 | 0.4866 | 0.2924 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 64.70 | 19.50 | 487 | 5643 | 0.0869 | 0.2927 |
| MCF 10A-H2B-mCherry | Dasatinib | 1.7783 | 32.20 | 19.50 | 663 | 2123 | 0.3126 | 0.2930 |
| MCF 10A-H2B-mCherry | Vorinostat | 5.6234 | 90.40 | 19.50 | 375 | 6097 | 0.0615 | 0.2931 |
| MCF 10A-H2B-mCherry | Etoposide | 1 | 94.30 | 19.50 | 784 | 6154 | 0.1273 | 0.2934 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 36.20 | 19.50 | 438 | 2641 | 0.1658 | 0.2934 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 68.70 | 19.50 | 473 | 5743 | 0.0832 | 0.2935 |
| MCF 10A-H2B-mCherry | Taxol | 0.0018 | 48.00 | 19.50 | 1368 | 4441 | 0.3084 | 0.2935 |
| MCF 10A-H2B-mCherry | Vorinostat | 3.1623 | 82.50 | 19.50 | 541 | 6031 | 0.0899 | 0.2957 |
| MCF 10A-H2B-mCherry | Dasatinib | 10 | 59.80 | 19.50 | 401 | 5578 | 0.0726 | 0.2964 |
| MCF 10A-H2B-mCherry | Vorinostat | 3.1623 | 92.30 | 19.50 | 588 | 6153 | 0.0957 | 0.2975 |
| MCF 10A-H2B-mCherry | Taxol | 0.031623 | 16.50 | 19.50 | 243 | 626 | 0.3895 | 0.2979 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 90.40 | 19.50 | 527 | 6097 | 0.0865 | 0.2983 |
| MCF 10A-H2B-mCherry | Dasatinib | 10 | 57.80 | 19.50 | 405 | 5483 | 0.0746 | 0.2992 |
| MCF 10A-H2B-mCherry | Taxol | 0.0031623 | 36.20 | 19.50 | 731 | 2641 | 0.2770 | 0.2998 |
| MCF 10A-H2B-mCherry | Dasatinib | 1.7783 | 36.20 | 19.50 | 747 | 2641 | 0.2831 | 0.3013 |
| MCF 10A-H2B-mCherry | Vorinostat | 10 | 20.40 | 19.50 | 344 | 951 | 0.3644 | 0.3034 |
| MCF 10A-H2B-mCherry | Vorinostat | 5.6234 | 36.20 | 19.50 | 384 | 2641 | 0.1456 | 0.3049 |
| MCF 10A-H2B-mCherry | Vorinostat | 5.6234 | 94.30 | 19.50 | 383 | 6154 | 0.0622 | 0.3065 |
| MCF 10A-H2B-mCherry | Taxol | 0.0031623 | 34.20 | 19.50 | 759 | 2452 | 0.3097 | 0.3067 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 92.30 | 19.50 | 511 | 6153 | 0.0830 | 0.3068 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 62.80 | 19.50 | 495 | 5586 | 0.0889 | 0.3071 |