LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 5 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 2. - Dataset (ID:20313)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Alpelisib | 10 | 64.70 | 19.50 | 3848 | 5643 | 0.6896 | 0.8613 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.031667 | 38.10 | 19.50 | 2441 | 2867 | 0.8518 | 0.8614 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 28.30 | 19.50 | 1644 | 1665 | 0.9877 | 0.8616 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 51.90 | 19.50 | 4340 | 4974 | 0.8707 | 0.8621 |
| MCF 10A-H2B-mCherry | Neratinib | 0.018 | 62.80 | 19.50 | 5270 | 5586 | 0.9459 | 0.8622 |
| MCF 10A-H2B-mCherry | Neratinib | 0.1 | 76.60 | 19.50 | 4281 | 5898 | 0.7269 | 0.8626 |
| MCF 10A-H2B-mCherry | Etoposide | 0.0033333 | 53.90 | 19.50 | 4554 | 5154 | 0.8752 | 0.8627 |
| MCF 10A-H2B-mCherry | Taxol | 0.00033333 | 40.10 | 19.50 | 2729 | 3104 | 0.8805 | 0.8627 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.31623 | 76.60 | 19.50 | 6671 | 5898 | 1.1230 | 0.8628 |
| MCF 10A-H2B-mCherry | Etoposide | 0.01 | 46.00 | 19.50 | 3587 | 4146 | 0.8650 | 0.8632 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 14.50 | 19.50 | 735 | 537 | 1.3667 | 0.8635 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.031667 | 34.20 | 19.50 | 2122 | 2452 | 0.8665 | 0.8636 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.1 | 80.50 | 19.50 | 6520 | 6018 | 1.0828 | 0.8636 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.031667 | 44.00 | 19.50 | 3206 | 3824 | 0.8385 | 0.8636 |
| MCF 10A-H2B-mCherry | Neratinib | 0.018 | 64.70 | 19.50 | 5412 | 5643 | 0.9603 | 0.8637 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.31623 | 55.90 | 19.50 | 4622 | 5348 | 0.8513 | 0.8638 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.31623 | 51.90 | 19.50 | 4142 | 4974 | 0.8262 | 0.8643 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 94.30 | 19.50 | 6320 | 6154 | 1.0244 | 0.8643 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 55.90 | 19.50 | 4755 | 5348 | 0.8873 | 0.8644 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 74.60 | 19.50 | 3748 | 5927 | 0.6359 | 0.8644 |
| MCF 10A-H2B-mCherry | Neratinib | 0.018 | 72.60 | 19.50 | 5764 | 5854 | 0.9820 | 0.8646 |
| MCF 10A-H2B-mCherry | Alpelisib | 10 | 72.60 | 19.50 | 4169 | 5854 | 0.7147 | 0.8647 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.031667 | 40.10 | 19.50 | 2650 | 3104 | 0.8536 | 0.8650 |
| MCF 10A-H2B-mCherry | Etoposide | 0.018333 | 51.90 | 19.50 | 3901 | 4974 | 0.7897 | 0.8654 |
| MCF 10A-H2B-mCherry | Etoposide | 0.018333 | 30.30 | 19.50 | 1588 | 1887 | 0.8418 | 0.8657 |