LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 5 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 2. - Dataset (ID:20313)
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Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|
MCF 10A-H2B-mCherry | Taxol | 0.031623 | 22.40 | 19.50 | 147 | 1150 | 0.1300 | 0.1286 |
MCF 10A-H2B-mCherry | Vorinostat | 10 | 90.40 | 19.50 | 282 | 6097 | 0.0464 | 0.1295 |
MCF 10A-H2B-mCherry | Taxol | 0.0031623 | 59.80 | 19.50 | 275 | 5578 | 0.0480 | 0.1297 |
MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 51.90 | 19.50 | 372 | 4974 | 0.0751 | 0.1299 |
MCF 10A-H2B-mCherry | Vorinostat | 10 | 78.50 | 19.50 | 274 | 5949 | 0.0462 | 0.1301 |
MCF 10A-H2B-mCherry | Vorinostat | 10 | 76.60 | 19.50 | 275 | 5898 | 0.0467 | 0.1304 |
MCF 10A-H2B-mCherry | Vorinostat | 10 | 82.50 | 19.50 | 282 | 6031 | 0.0468 | 0.1314 |
MCF 10A-H2B-mCherry | Vorinostat | 10 | 44.00 | 19.50 | 258 | 3824 | 0.0677 | 0.1320 |
MCF 10A-H2B-mCherry | Vorinostat | 10 | 92.30 | 19.50 | 284 | 6153 | 0.0463 | 0.1341 |
MCF 10A-H2B-mCherry | Vorinostat | 10 | 86.40 | 19.50 | 281 | 6081 | 0.0463 | 0.1352 |
MCF 10A-H2B-mCherry | Vorinostat | 10 | 42.10 | 19.50 | 265 | 3461 | 0.0767 | 0.1359 |
MCF 10A-H2B-mCherry | Dasatinib | 10 | 88.40 | 19.50 | 266 | 6064 | 0.0439 | 0.1364 |
MCF 10A-H2B-mCherry | Vorinostat | 10 | 80.50 | 19.50 | 280 | 6018 | 0.0467 | 0.1374 |
MCF 10A-H2B-mCherry | Taxol | 0.01 | 28.30 | 19.50 | 223 | 1665 | 0.1338 | 0.1377 |
MCF 10A-H2B-mCherry | Etoposide | 10 | 92.30 | 19.50 | 318 | 6153 | 0.0517 | 0.1389 |
MCF 10A-H2B-mCherry | Vorinostat | 10 | 94.30 | 19.50 | 284 | 6154 | 0.0463 | 0.1389 |
MCF 10A-H2B-mCherry | Etoposide | 10 | 90.40 | 19.50 | 317 | 6097 | 0.0521 | 0.1394 |
MCF 10A-H2B-mCherry | Taxol | 0.0031623 | 57.80 | 19.50 | 297 | 5483 | 0.0526 | 0.1404 |
MCF 10A-H2B-mCherry | Taxol | 0.01 | 26.30 | 19.50 | 247 | 1491 | 0.1648 | 0.1409 |
MCF 10A-H2B-mCherry | Taxol | 0.0018 | 82.50 | 19.50 | 516 | 6031 | 0.0865 | 0.1431 |
MCF 10A-H2B-mCherry | Etoposide | 10 | 70.70 | 19.50 | 321 | 5784 | 0.0557 | 0.1446 |
MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 50.00 | 19.50 | 372 | 4744 | 0.0786 | 0.1448 |
MCF 10A-H2B-mCherry | Dasatinib | 10 | 84.40 | 19.50 | 288 | 6038 | 0.0478 | 0.1459 |
MCF 10A-H2B-mCherry | Etoposide | 10 | 57.80 | 19.50 | 331 | 5483 | 0.0605 | 0.1468 |
MCF 10A-H2B-mCherry | Taxol | 0.0031623 | 55.90 | 19.50 | 316 | 5348 | 0.0578 | 0.1473 |