LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 5 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 2. - Dataset (ID:20313)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 88.40 | 19.50 | 7139 | 6064 | 1.1770 | 0.8440 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 84.40 | 19.50 | 7134 | 6038 | 1.1830 | 0.9496 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 86.40 | 19.50 | 7119 | 6081 | 1.1718 | 0.9404 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 76.60 | 19.50 | 7096 | 5898 | 1.1929 | 0.9801 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 94.30 | 19.50 | 7074 | 6154 | 1.1499 | 0.6009 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 76.60 | 19.50 | 7044 | 5898 | 1.1943 | 0.9599 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 92.30 | 19.50 | 7043 | 6153 | 1.1450 | 0.7830 |
| MCF 10A-H2B-mCherry | Neratinib | 0.0053333 | 94.30 | 19.50 | 7025 | 6154 | 1.1423 | 0.6590 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 92.30 | 19.50 | 6971 | 6153 | 1.1331 | 0.5889 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 94.30 | 19.50 | 6969 | 6154 | 1.1328 | 0.6914 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.1 | 94.30 | 19.50 | 6924 | 6154 | 1.1261 | 0.7152 |
| MCF 10A-H2B-mCherry | Neratinib | 0.0053333 | 92.30 | 19.50 | 6882 | 6153 | 1.1188 | 0.6621 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 62.80 | 19.50 | 6876 | 5586 | 1.1979 | 0.8873 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.31623 | 82.50 | 19.50 | 6873 | 6031 | 1.1340 | 0.8206 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.31623 | 84.40 | 19.50 | 6872 | 6038 | 1.1346 | 0.8057 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.31623 | 86.40 | 19.50 | 6868 | 6081 | 1.1272 | 0.7898 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 74.60 | 19.50 | 6867 | 5927 | 1.1456 | 0.9739 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 90.40 | 19.50 | 6842 | 6097 | 1.1222 | 0.5863 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.1 | 92.30 | 19.50 | 6837 | 6153 | 1.1115 | 0.7459 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.31623 | 92.30 | 19.50 | 6835 | 6153 | 1.1115 | 0.9037 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 74.60 | 19.50 | 6819 | 5927 | 1.1514 | 0.9500 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.31623 | 94.30 | 19.50 | 6818 | 6154 | 1.1092 | 0.8822 |
| MCF 10A-H2B-mCherry | Neratinib | 0.031623 | 92.30 | 19.50 | 6818 | 6153 | 1.1092 | 0.7552 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.31623 | 90.40 | 19.50 | 6816 | 6097 | 1.1183 | 0.7437 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.31623 | 80.50 | 19.50 | 6813 | 6018 | 1.1255 | 0.8249 |