LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 5 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 2. - Dataset (ID:20313)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Taxol | 0.1 | 90.40 | 19.50 | 9 | 6097 | 0.0015 | -0.2309 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.0010833 | 90.40 | 19.50 | 5949 | 6097 | 0.9758 | 0.6247 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.31623 | 90.40 | 19.50 | 6816 | 6097 | 1.1183 | 0.7437 |
| MCF 10A-H2B-mCherry | Neratinib | 0.56234 | 90.40 | 19.50 | 607 | 6097 | 0.0996 | 0.3709 |
| MCF 10A-H2B-mCherry | Taxol | 0.31623 | 90.40 | 19.50 | 1 | 6097 | 0.0002 | -0.3005 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 90.40 | 19.50 | 6277 | 6097 | 1.0298 | 0.5774 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.031667 | 90.40 | 19.50 | 6443 | 6097 | 1.0568 | 0.6131 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.0033333 | 90.40 | 19.50 | 6488 | 6097 | 1.0643 | 0.5925 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.31623 | 90.40 | 19.50 | 3229 | 6097 | 0.5296 | 0.7663 |
| MCF 10A-H2B-mCherry | 0 | 90.40 | 19.50 | 6334 | 6097 | 1.0390 | 0.6151 | |
| MCF 10A-H2B-mCherry | Palbociclib | 0.17783 | 90.40 | 19.50 | 4728 | 6097 | 0.7756 | 0.7663 |
| MCF 10A-H2B-mCherry | Neratinib | 0.17783 | 90.40 | 19.50 | 2995 | 6097 | 0.4914 | 0.6777 |
| MCF 10A-H2B-mCherry | Taxol | 0.017783 | 90.40 | 19.50 | 18 | 6097 | 0.0030 | -0.2037 |
| MCF 10A-H2B-mCherry | Taxol | 0.031623 | 90.40 | 19.50 | 22 | 6097 | 0.0037 | -0.1556 |
| MCF 10A-H2B-mCherry | Etoposide | 0.01 | 90.40 | 19.50 | 5677 | 6097 | 0.9311 | 0.6587 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.01 | 90.40 | 19.50 | 6055 | 6097 | 0.9932 | 0.6069 |
| MCF 10A-H2B-mCherry | Alpelisib | 3.1623 | 90.40 | 19.50 | 5429 | 6097 | 0.8905 | 0.6809 |
| MCF 10A-H2B-mCherry | Etoposide | 0.056667 | 90.40 | 19.50 | 5875 | 6097 | 0.9638 | 0.4926 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.1 | 90.40 | 19.50 | 4134 | 6097 | 0.6781 | 0.7235 |
| MCF 10A-H2B-mCherry | Taxol | 0.01 | 90.40 | 19.50 | 10 | 6097 | 0.0017 | -0.2225 |
| MCF 10A-H2B-mCherry | Neratinib | 0.0013333 | 90.40 | 19.50 | 5976 | 6097 | 0.9803 | 0.6330 |
| MCF 10A-H2B-mCherry | Etoposide | 0.31623 | 90.40 | 19.50 | 2904 | 6097 | 0.4764 | 0.5297 |
| MCF 10A-H2B-mCherry | Taxol | 0.0031623 | 90.40 | 19.50 | 31 | 6097 | 0.0051 | -0.0647 |
| MCF 10A-H2B-mCherry | Dasatinib | 1.7783 | 90.40 | 19.50 | 2687 | 6097 | 0.4408 | 0.4501 |
| MCF 10A-H2B-mCherry | Etoposide | 0.56234 | 90.40 | 19.50 | 1429 | 6097 | 0.2344 | 0.4178 |