LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 5 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 2. - Dataset (ID:20313)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Taxol | 0.00013333 | 2.70 | 19.50 | 238 | 163 | 1.4688 | 0.5916 |
| MCF 10A-H2B-mCherry | Etoposide | 0.0010833 | 2.70 | 19.50 | 247 | 163 | 1.4658 | 0.5955 |
| MCF 10A-H2B-mCherry | Etoposide | 0.031667 | 2.70 | 19.50 | 239 | 163 | 1.4630 | 0.6054 |
| MCF 10A-H2B-mCherry | Neratinib | 0.0013333 | 2.70 | 19.50 | 243 | 163 | 1.4611 | 0.7076 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.0033333 | 2.70 | 19.50 | 235 | 163 | 1.4573 | 0.7034 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.0033333 | 2.70 | 19.50 | 234 | 163 | 1.4529 | 0.7260 |
| MCF 10A-H2B-mCherry | Palbociclib | 5.6234 | 2.70 | 19.50 | 235 | 163 | 1.4527 | 0.6476 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 4.60 | 19.50 | 419 | 295 | 1.4357 | 0.5386 |
| MCF 10A-H2B-mCherry | Vorinostat | 1 | 2.70 | 19.50 | 232 | 163 | 1.4347 | 0.7130 |
| MCF 10A-H2B-mCherry | Etoposide | 1.7783 | 2.70 | 19.50 | 239 | 163 | 1.4337 | 0.6009 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 2.70 | 19.50 | 234 | 163 | 1.4322 | 0.6589 |
| MCF 10A-H2B-mCherry | Neratinib | 0.31623 | 2.70 | 19.50 | 239 | 163 | 1.4305 | 0.5999 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.56234 | 2.70 | 19.50 | 234 | 163 | 1.4290 | 0.6605 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 4.60 | 19.50 | 414 | 295 | 1.4225 | 0.5343 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.01 | 2.70 | 19.50 | 234 | 163 | 1.4172 | 0.6174 |
| MCF 10A-H2B-mCherry | Etoposide | 0.018333 | 2.70 | 19.50 | 229 | 163 | 1.4150 | 0.6417 |
| MCF 10A-H2B-mCherry | Etoposide | 1 | 2.70 | 19.50 | 228 | 163 | 1.4058 | 0.6641 |
| MCF 10A-H2B-mCherry | Neratinib | 0.56234 | 4.60 | 19.50 | 407 | 295 | 1.3874 | 0.5763 |
| MCF 10A-H2B-mCherry | Neratinib | 0.0053333 | 2.70 | 19.50 | 222 | 163 | 1.3866 | 0.6075 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.56234 | 2.70 | 19.50 | 226 | 163 | 1.3811 | 0.5817 |
| MCF 10A-H2B-mCherry | Alpelisib | 1 | 2.70 | 19.50 | 233 | 163 | 1.3790 | 0.5442 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.31623 | 2.70 | 19.50 | 227 | 163 | 1.3761 | 0.5776 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 16.50 | 19.50 | 857 | 626 | 1.3742 | 0.9183 |
| MCF 10A-H2B-mCherry | Dasatinib | 10 | 2.70 | 19.50 | 228 | 163 | 1.3734 | 0.5450 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.17783 | 2.70 | 19.50 | 228 | 163 | 1.3707 | 0.5734 |