LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 5 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 2. - Dataset (ID:20313)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Taxol | 0.00033333 | 2.70 | 19.50 | 190 | 163 | 1.1373 | 0.5371 |
| MCF 10A-H2B-mCherry | Taxol | 0.00013333 | 14.50 | 19.50 | 611 | 537 | 1.1368 | 0.5762 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.0033333 | 12.50 | 19.50 | 563 | 495 | 1.1366 | 0.6069 |
| MCF 10A-H2B-mCherry | 0 | 4.60 | 19.50 | 334 | 295 | 1.1360 | 0.4798 | |
| MCF 10A-H2B-mCherry | Etoposide | 0.01 | 14.50 | 19.50 | 610 | 537 | 1.1347 | 0.7345 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.31623 | 84.40 | 19.50 | 6872 | 6038 | 1.1346 | 0.8057 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.31623 | 82.50 | 19.50 | 6873 | 6031 | 1.1340 | 0.8206 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 92.30 | 19.50 | 6971 | 6153 | 1.1331 | 0.5889 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 94.30 | 19.50 | 6969 | 6154 | 1.1328 | 0.6914 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 16.50 | 19.50 | 702 | 626 | 1.1323 | 0.6641 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.17783 | 2.70 | 19.50 | 181 | 163 | 1.1313 | 0.5233 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 72.60 | 19.50 | 6616 | 5854 | 1.1310 | 0.9461 |
| MCF 10A-H2B-mCherry | Neratinib | 0.0053333 | 4.60 | 19.50 | 331 | 295 | 1.1305 | 0.4724 |
| MCF 10A-H2B-mCherry | Etoposide | 0.031667 | 16.50 | 19.50 | 704 | 626 | 1.1302 | 0.7332 |
| MCF 10A-H2B-mCherry | Etoposide | 0.1 | 12.50 | 19.50 | 559 | 495 | 1.1296 | 0.6604 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.0010833 | 6.60 | 19.50 | 441 | 390 | 1.1289 | 0.4566 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.31623 | 86.40 | 19.50 | 6868 | 6081 | 1.1272 | 0.7898 |
| MCF 10A-H2B-mCherry | Neratinib | 0.0013333 | 6.60 | 19.50 | 440 | 390 | 1.1272 | 0.5854 |
| MCF 10A-H2B-mCherry | Neratinib | 0.17783 | 6.60 | 19.50 | 440 | 390 | 1.1270 | 0.4966 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.1 | 14.50 | 19.50 | 605 | 537 | 1.1270 | 0.7335 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.31623 | 78.50 | 19.50 | 6745 | 5949 | 1.1263 | 0.8476 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.1 | 94.30 | 19.50 | 6924 | 6154 | 1.1261 | 0.7152 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 72.60 | 19.50 | 6672 | 5854 | 1.1260 | 0.9661 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.31623 | 80.50 | 19.50 | 6813 | 6018 | 1.1255 | 0.8249 |
| MCF 10A-H2B-mCherry | Etoposide | 0.0010833 | 4.60 | 19.50 | 335 | 295 | 1.1253 | 0.4615 |