LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 5 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 2. - Dataset (ID:20313)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Vorinostat | 0.1 | 30.30 | 19.50 | 1994 | 1887 | 1.0568 | 0.9528 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.1 | 32.20 | 19.50 | 2222 | 2123 | 1.0456 | 0.9524 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.31623 | 66.70 | 19.50 | 5404 | 5728 | 0.9419 | 0.9503 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.31623 | 74.60 | 19.50 | 6073 | 5927 | 1.0207 | 0.9503 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.31623 | 82.50 | 19.50 | 6639 | 6031 | 1.0976 | 0.9502 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 74.60 | 19.50 | 6819 | 5927 | 1.1514 | 0.9500 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 66.70 | 19.50 | 5909 | 5728 | 1.0142 | 0.9499 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 84.40 | 19.50 | 7134 | 6038 | 1.1830 | 0.9496 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.31623 | 80.50 | 19.50 | 6507 | 6018 | 1.0778 | 0.9491 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 88.40 | 19.50 | 7418 | 6064 | 1.2225 | 0.9489 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 18.40 | 19.50 | 1030 | 775 | 1.3323 | 0.9479 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.31623 | 70.70 | 19.50 | 5704 | 5784 | 0.9820 | 0.9468 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.31623 | 64.70 | 19.50 | 5122 | 5643 | 0.9091 | 0.9461 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 72.60 | 19.50 | 6616 | 5854 | 1.1310 | 0.9461 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.31623 | 84.40 | 19.50 | 6691 | 6038 | 1.1060 | 0.9453 |
| MCF 10A-H2B-mCherry | Neratinib | 0.01 | 66.70 | 19.50 | 6038 | 5728 | 1.0574 | 0.9445 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.1 | 36.20 | 19.50 | 2668 | 2641 | 1.0084 | 0.9440 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.1 | 40.10 | 19.50 | 3099 | 3104 | 0.9974 | 0.9437 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.1 | 38.10 | 19.50 | 2889 | 2867 | 1.0060 | 0.9436 |
| MCF 10A-H2B-mCherry | Neratinib | 0.01 | 68.70 | 19.50 | 6148 | 5743 | 1.0728 | 0.9430 |
| MCF 10A-H2B-mCherry | Etoposide | 0.56234 | 24.30 | 19.50 | 1124 | 1322 | 0.8533 | 0.9429 |
| MCF 10A-H2B-mCherry | Etoposide | 0.56234 | 20.40 | 19.50 | 849 | 951 | 0.8869 | 0.9415 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.1 | 34.20 | 19.50 | 2461 | 2452 | 1.0001 | 0.9414 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.1 | 42.10 | 19.50 | 3367 | 3461 | 0.9711 | 0.9404 |
| MCF 10A-H2B-mCherry | Neratinib | 0.018 | 16.50 | 19.50 | 792 | 626 | 1.2747 | 0.9404 |