LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 5 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 2. - Dataset (ID:20313)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 51.90 | 19.50 | 4340 | 4974 | 0.8707 | 0.8621 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 28.30 | 19.50 | 1644 | 1665 | 0.9877 | 0.8616 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.031667 | 38.10 | 19.50 | 2441 | 2867 | 0.8518 | 0.8614 |
| MCF 10A-H2B-mCherry | Alpelisib | 10 | 64.70 | 19.50 | 3848 | 5643 | 0.6896 | 0.8613 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.031667 | 50.00 | 19.50 | 3965 | 4744 | 0.8362 | 0.8612 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.031667 | 46.00 | 19.50 | 3523 | 4146 | 0.8499 | 0.8611 |
| MCF 10A-H2B-mCherry | Etoposide | 0.0033333 | 55.90 | 19.50 | 4770 | 5348 | 0.8816 | 0.8606 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.1 | 82.50 | 19.50 | 6629 | 6031 | 1.0983 | 0.8605 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 28.30 | 19.50 | 1509 | 1665 | 0.9059 | 0.8602 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 55.90 | 19.50 | 5711 | 5348 | 1.0425 | 0.8600 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 57.80 | 19.50 | 4950 | 5483 | 0.9025 | 0.8599 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 48.00 | 19.50 | 3604 | 4441 | 0.8115 | 0.8598 |
| MCF 10A-H2B-mCherry | Etoposide | 0.01 | 38.10 | 19.50 | 2536 | 2867 | 0.8878 | 0.8596 |
| MCF 10A-H2B-mCherry | Etoposide | 0.01 | 62.80 | 19.50 | 5411 | 5586 | 0.9558 | 0.8594 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 30.30 | 19.50 | 1717 | 1887 | 0.9102 | 0.8593 |
| MCF 10A-H2B-mCherry | Alpelisib | 1.7783 | 48.00 | 19.50 | 3523 | 4441 | 0.7942 | 0.8592 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 50.00 | 19.50 | 3862 | 4744 | 0.8139 | 0.8584 |
| MCF 10A-H2B-mCherry | Etoposide | 0.01 | 30.30 | 19.50 | 1717 | 1887 | 0.9102 | 0.8584 |
| MCF 10A-H2B-mCherry | Etoposide | 0.01 | 57.80 | 19.50 | 5140 | 5483 | 0.9219 | 0.8582 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.031667 | 51.90 | 19.50 | 4074 | 4974 | 0.8197 | 0.8578 |
| MCF 10A-H2B-mCherry | Alpelisib | 1.7783 | 80.50 | 19.50 | 5742 | 6018 | 0.9527 | 0.8578 |
| MCF 10A-H2B-mCherry | Alpelisib | 1.7783 | 44.00 | 19.50 | 2939 | 3824 | 0.7677 | 0.8576 |
| MCF 10A-H2B-mCherry | Neratinib | 0.018 | 76.60 | 19.50 | 5871 | 5898 | 0.9938 | 0.8576 |
| MCF 10A-H2B-mCherry | Alpelisib | 10 | 66.70 | 19.50 | 3926 | 5728 | 0.6924 | 0.8571 |
| MCF 10A-H2B-mCherry | Alpelisib | 10 | 70.70 | 19.50 | 4028 | 5784 | 0.7012 | 0.8569 |