LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 4 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 1. - Dataset (ID:20312)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Etoposide | 10 | 87.50 | 770.96 | 773 | 12567 | 0.0615 | 0.0006 |
| MCF 10A-H2B-mCherry | Neratinib | 0.0033333 | 87.50 | 770.96 | 11788 | 12567 | 0.9381 | 0.9670 |
| MCF 10A-H2B-mCherry | Neratinib | 0.0053333 | 87.50 | 770.96 | 13241 | 12567 | 1.0536 | 1.0261 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.01 | 87.50 | 770.96 | 10506 | 12567 | 0.8362 | 0.9092 |
| MCF 10A-H2B-mCherry | Dasatinib | 1 | 87.50 | 770.96 | 5115 | 12567 | 0.4073 | 0.5800 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.0033333 | 87.50 | 770.96 | 11987 | 12567 | 0.9539 | 0.9736 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.1 | 87.50 | 770.96 | 12268 | 12567 | 0.9763 | 0.9866 |
| MCF 10A-H2B-mCherry | Alpelisib | 1.7783 | 87.50 | 770.96 | 9269 | 12567 | 0.7375 | 0.8532 |
| MCF 10A-H2B-mCherry | Alpelisib | 10 | 87.50 | 770.96 | 6863 | 12567 | 0.5462 | 0.7163 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.031667 | 87.50 | 770.96 | 9867 | 12567 | 0.7852 | 0.8753 |
| MCF 10A-H2B-mCherry | Alpelisib | 5.6234 | 87.50 | 770.96 | 9289 | 12567 | 0.7390 | 0.8532 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.01 | 87.50 | 770.96 | 13230 | 12567 | 1.0529 | 1.0226 |
| MCF 10A-H2B-mCherry | 0 | 87.50 | 770.96 | 12125 | 12567 | 0.9648 | 0.9748 | |
| MCF 10A-H2B-mCherry | Alpelisib | 3.1623 | 87.50 | 770.96 | 10049 | 12567 | 0.7997 | 0.8902 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.056667 | 87.50 | 770.96 | 9167 | 12567 | 0.7297 | 0.8409 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.031667 | 87.50 | 770.96 | 12815 | 12567 | 1.0198 | 1.0090 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.0010833 | 87.50 | 770.96 | 12782 | 12567 | 1.0173 | 1.0029 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.31623 | 87.50 | 770.96 | 10679 | 12567 | 0.8498 | 0.9204 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.17783 | 87.50 | 770.96 | 6652 | 12567 | 0.5292 | 0.7054 |
| MCF 10A-H2B-mCherry | Etoposide | 0.1 | 87.50 | 770.96 | 10463 | 12567 | 0.8325 | 0.9087 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.1 | 87.50 | 770.96 | 6743 | 12567 | 0.5365 | 0.7132 |
| MCF 10A-H2B-mCherry | Alpelisib | 1 | 87.50 | 770.96 | 11455 | 12567 | 0.9116 | 0.9498 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.56234 | 87.50 | 770.96 | 6185 | 12567 | 0.4922 | 0.6761 |
| MCF 10A-H2B-mCherry | Neratinib | 0.17783 | 87.50 | 770.96 | 5369 | 12567 | 0.4273 | 0.6108 |
| MCF 10A-H2B-mCherry | Neratinib | 0.1 | 87.50 | 770.96 | 6742 | 12567 | 0.5365 | 0.7122 |