LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 4 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 1. - Dataset (ID:20312)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Dasatinib | 3.1623 | 2.90 | 770.96 | 787 | 886 | 0.8886 | 0.1379 |
| MCF 10A-H2B-mCherry | Neratinib | 0.031623 | 2.90 | 770.96 | 905 | 886 | 1.0221 | 1.3764 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.018333 | 2.90 | 770.96 | 885 | 886 | 0.9987 | 1.2077 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 2.90 | 770.96 | 857 | 886 | 0.9688 | 1.0455 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 2.90 | 770.96 | 871 | 886 | 0.9824 | 0.8118 |
| MCF 10A-H2B-mCherry | Palbociclib | 3.1623 | 2.90 | 770.96 | 897 | 886 | 1.0118 | 1.1079 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.01 | 2.90 | 770.96 | 914 | 886 | 1.0328 | 1.5960 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.0033333 | 2.90 | 770.96 | 878 | 886 | 0.9921 | 1.0506 |
| MCF 10A-H2B-mCherry | Taxol | 0.017783 | 2.90 | 770.96 | 679 | 886 | 0.7671 | -0.4475 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 2.90 | 770.96 | 855 | 886 | 0.9653 | 0.6660 |
| MCF 10A-H2B-mCherry | Taxol | 0.0056234 | 2.90 | 770.96 | 853 | 886 | 0.9634 | 0.8814 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.1 | 2.90 | 770.96 | 811 | 886 | 0.9161 | 0.3321 |
| MCF 10A-H2B-mCherry | Taxol | 0.00013333 | 2.90 | 770.96 | 919 | 886 | 1.0363 | 1.4368 |
| MCF 10A-H2B-mCherry | Vorinostat | 3.1623 | 2.90 | 770.96 | 895 | 886 | 1.0120 | 1.3826 |
| MCF 10A-H2B-mCherry | Taxol | 0.00033333 | 2.90 | 770.96 | 855 | 886 | 0.9655 | 0.6809 |
| MCF 10A-H2B-mCherry | Neratinib | 0.0033333 | 2.90 | 770.96 | 939 | 886 | 1.0622 | 2.2869 |
| MCF 10A-H2B-mCherry | Etoposide | 0.0033333 | 2.90 | 770.96 | 887 | 886 | 1.0010 | 0.9868 |
| MCF 10A-H2B-mCherry | Etoposide | 0.56234 | 2.90 | 770.96 | 897 | 886 | 1.0119 | 1.1020 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.56234 | 2.90 | 770.96 | 928 | 886 | 1.0486 | 1.9019 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.01 | 2.90 | 770.96 | 880 | 886 | 0.9929 | 0.9591 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.31623 | 2.90 | 770.96 | 800 | 886 | 0.9030 | 0.2194 |
| MCF 10A-H2B-mCherry | Taxol | 0.0031623 | 2.90 | 770.96 | 810 | 886 | 0.9138 | 0.3057 |
| MCF 10A-H2B-mCherry | Palbociclib | 5.6234 | 2.90 | 770.96 | 887 | 886 | 1.0024 | 1.4153 |