LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 4 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 1. - Dataset (ID:20312)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Etoposide | 1 | 83.10 | 770.96 | 1733 | 12002 | 0.1444 | 0.2222 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.0010833 | 83.10 | 770.96 | 12325 | 12002 | 1.0267 | 1.0092 |
| MCF 10A-H2B-mCherry | Etoposide | 0.1 | 83.10 | 770.96 | 9824 | 12002 | 0.8186 | 0.8997 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.1 | 83.10 | 770.96 | 11679 | 12002 | 0.9729 | 0.9851 |
| MCF 10A-H2B-mCherry | Neratinib | 0.0053333 | 83.10 | 770.96 | 12537 | 12002 | 1.0445 | 1.0221 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 83.10 | 770.96 | 10395 | 12002 | 0.8661 | 0.9271 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.17783 | 83.10 | 770.96 | 6231 | 12002 | 0.5190 | 0.6922 |
| MCF 10A-H2B-mCherry | Etoposide | 0.01 | 83.10 | 770.96 | 10981 | 12002 | 0.9147 | 0.9526 |
| MCF 10A-H2B-mCherry | Etoposide | 0.056667 | 83.10 | 770.96 | 10895 | 12002 | 0.9080 | 0.9463 |
| MCF 10A-H2B-mCherry | Alpelisib | 3.1623 | 83.10 | 770.96 | 9506 | 12002 | 0.7920 | 0.8842 |
| MCF 10A-H2B-mCherry | Neratinib | 0.17783 | 83.10 | 770.96 | 4843 | 12002 | 0.4035 | 0.5816 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.56234 | 83.10 | 770.96 | 5858 | 12002 | 0.4880 | 0.6679 |
| MCF 10A-H2B-mCherry | Taxol | 0.01 | 83.10 | 770.96 | 389 | 12002 | 0.0325 | -0.1607 |
| MCF 10A-H2B-mCherry | Taxol | 0.017783 | 83.10 | 770.96 | 176 | 12002 | 0.0147 | -0.3197 |
| MCF 10A-H2B-mCherry | Taxol | 0.031623 | 83.10 | 770.96 | 209 | 12002 | 0.0174 | -0.2814 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.056667 | 83.10 | 770.96 | 8997 | 12002 | 0.7494 | 0.8536 |
| MCF 10A-H2B-mCherry | Neratinib | 0.1 | 83.10 | 770.96 | 6208 | 12002 | 0.5172 | 0.6923 |
| MCF 10A-H2B-mCherry | Dasatinib | 10 | 83.10 | 770.96 | 731 | 12002 | 0.0609 | -0.0170 |
| MCF 10A-H2B-mCherry | Etoposide | 0.56234 | 83.10 | 770.96 | 3059 | 12002 | 0.2547 | 0.4065 |
| MCF 10A-H2B-mCherry | Alpelisib | 1 | 83.10 | 770.96 | 11015 | 12002 | 0.9176 | 0.9536 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.0033333 | 83.10 | 770.96 | 12536 | 12002 | 1.0444 | 1.0219 |
| MCF 10A-H2B-mCherry | Taxol | 0.0031623 | 83.10 | 770.96 | 1844 | 12002 | 0.1536 | 0.2387 |
| MCF 10A-H2B-mCherry | Taxol | 0.0056234 | 83.10 | 770.96 | 842 | 12002 | 0.0702 | 0.0225 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.31623 | 83.10 | 770.96 | 3243 | 12002 | 0.2702 | 0.4323 |
| MCF 10A-H2B-mCherry | Taxol | 0.0018 | 83.10 | 770.96 | 5785 | 12002 | 0.4819 | 0.6609 |