LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 4 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 1. - Dataset (ID:20312)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Taxol | 0.31623 | 87.50 | 770.96 | 54 | 12567 | 0.0043 | -0.4860 |
| MCF 10A-H2B-mCherry | Dasatinib | 3.1623 | 87.50 | 770.96 | 1665 | 12567 | 0.1325 | 0.2091 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 87.50 | 770.96 | 1454 | 12567 | 0.1157 | 0.1688 |
| MCF 10A-H2B-mCherry | Alpelisib | 1 | 87.50 | 770.96 | 11455 | 12567 | 0.9116 | 0.9498 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.01 | 87.50 | 770.96 | 10718 | 12567 | 0.8528 | 0.9206 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.31623 | 87.50 | 770.96 | 6310 | 12567 | 0.5022 | 0.6795 |
| MCF 10A-H2B-mCherry | Neratinib | 0.0053333 | 87.50 | 770.96 | 13241 | 12567 | 1.0536 | 1.0261 |
| MCF 10A-H2B-mCherry | Neratinib | 0.56234 | 87.50 | 770.96 | 1766 | 12567 | 0.1406 | 0.2229 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 87.50 | 770.96 | 12164 | 12567 | 0.9679 | 0.9791 |
| MCF 10A-H2B-mCherry | Dasatinib | 1.7783 | 87.50 | 770.96 | 5112 | 12567 | 0.4068 | 0.5989 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.01 | 87.50 | 770.96 | 10506 | 12567 | 0.8362 | 0.9092 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 87.50 | 770.96 | 1754 | 12567 | 0.1396 | 0.2254 |
| MCF 10A-H2B-mCherry | Vorinostat | 1.7783 | 87.50 | 770.96 | 2559 | 12567 | 0.2037 | 0.3430 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.01 | 87.50 | 770.96 | 13230 | 12567 | 1.0529 | 1.0226 |
| MCF 10A-H2B-mCherry | Taxol | 0.001 | 87.50 | 770.96 | 9908 | 12567 | 0.7885 | 0.8806 |
| MCF 10A-H2B-mCherry | Trametinib | 0.031623 | 87.50 | 770.96 | 2058 | 12567 | 0.1638 | 0.2758 |
| MCF 10A-H2B-mCherry | Etoposide | 0.1 | 87.50 | 770.96 | 10463 | 12567 | 0.8325 | 0.9087 |
| MCF 10A-H2B-mCherry | Neratinib | 0.056234 | 87.50 | 770.96 | 9172 | 12567 | 0.7296 | 0.8449 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.0010833 | 87.50 | 770.96 | 12367 | 12567 | 0.9841 | 0.9917 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.56234 | 87.50 | 770.96 | 3744 | 12567 | 0.2980 | 0.4774 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.056667 | 87.50 | 770.96 | 9527 | 12567 | 0.7582 | 0.8600 |
| MCF 10A-H2B-mCherry | Etoposide | 1 | 87.50 | 770.96 | 1747 | 12567 | 0.1390 | 0.2203 |
| MCF 10A-H2B-mCherry | Alpelisib | 5.6234 | 87.50 | 770.96 | 9289 | 12567 | 0.7390 | 0.8532 |