LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 4 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 1. - Dataset (ID:20312)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 7.30 | 770.96 | 1050 | 1067 | 0.9848 | 0.9557 |
| MCF 10A-H2B-mCherry | Alpelisib | 1 | 7.30 | 770.96 | 1158 | 1067 | 1.0843 | 1.3805 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.031667 | 7.30 | 770.96 | 1118 | 1067 | 1.0475 | 1.2209 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.056667 | 7.30 | 770.96 | 1030 | 1067 | 0.9653 | 0.8546 |
| MCF 10A-H2B-mCherry | Etoposide | 0.031667 | 7.30 | 770.96 | 1078 | 1067 | 1.0101 | 1.0447 |
| MCF 10A-H2B-mCherry | Etoposide | 0.0033333 | 7.30 | 770.96 | 1089 | 1067 | 1.0200 | 1.0860 |
| MCF 10A-H2B-mCherry | Alpelisib | 3.1623 | 7.30 | 770.96 | 1004 | 1067 | 0.9420 | 0.7976 |
| MCF 10A-H2B-mCherry | Etoposide | 0.31623 | 7.30 | 770.96 | 1061 | 1067 | 0.9961 | 1.0377 |
| MCF 10A-H2B-mCherry | Neratinib | 0.056234 | 7.30 | 770.96 | 1071 | 1067 | 1.0056 | 1.0754 |
| MCF 10A-H2B-mCherry | Taxol | 0.017783 | 7.30 | 770.96 | 669 | 1067 | 0.6270 | -0.2570 |
| MCF 10A-H2B-mCherry | Neratinib | 0.031623 | 7.30 | 770.96 | 1049 | 1067 | 0.9833 | 0.9520 |
| MCF 10A-H2B-mCherry | Taxol | 0.0031623 | 7.30 | 770.96 | 1038 | 1067 | 0.9718 | 0.8770 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 7.30 | 770.96 | 814 | 1067 | 0.7638 | 0.1404 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.056667 | 7.30 | 770.96 | 1044 | 1067 | 0.9769 | 0.9007 |
| MCF 10A-H2B-mCherry | Alpelisib | 10 | 7.30 | 770.96 | 1036 | 1067 | 0.9706 | 0.8973 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.01 | 7.30 | 770.96 | 1063 | 1067 | 0.9964 | 0.9920 |
| MCF 10A-H2B-mCherry | Taxol | 0.0018 | 7.30 | 770.96 | 1169 | 1067 | 1.0942 | 1.4193 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.031667 | 7.30 | 770.96 | 1135 | 1067 | 1.0631 | 1.2831 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.0033333 | 7.30 | 770.96 | 1092 | 1067 | 1.0242 | 1.1249 |
| MCF 10A-H2B-mCherry | Taxol | 0.00053333 | 7.30 | 770.96 | 1028 | 1067 | 0.9622 | 0.8363 |
| MCF 10A-H2B-mCherry | Etoposide | 0.56234 | 7.30 | 770.96 | 1054 | 1067 | 0.9876 | 0.9485 |
| MCF 10A-H2B-mCherry | Neratinib | 0.17783 | 7.30 | 770.96 | 1065 | 1067 | 0.9987 | 1.0239 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.31623 | 7.30 | 770.96 | 1062 | 1067 | 0.9966 | 1.0164 |
| MCF 10A-H2B-mCherry | Etoposide | 0.17783 | 7.30 | 770.96 | 1106 | 1067 | 1.0369 | 1.1812 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.31623 | 7.30 | 770.96 | 967 | 1067 | 0.9068 | 0.6269 |