LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 4 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 1. - Dataset (ID:20312)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Vorinostat | 3.1623 | 14.10 | 770.96 | 939 | 1478 | 0.6355 | 0.2351 |
| MCF 10A-H2B-mCherry | Neratinib | 0.0033333 | 2.90 | 770.96 | 939 | 886 | 1.0622 | 2.2869 |
| MCF 10A-H2B-mCherry | Taxol | 0.00053333 | 5.10 | 770.96 | 939 | 984 | 0.9532 | 0.7303 |
| MCF 10A-H2B-mCherry | Taxol | 0.0056234 | 76.40 | 770.96 | 941 | 11184 | 0.0842 | 0.0526 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 5.10 | 770.96 | 941 | 984 | 0.9584 | 0.8616 |
| MCF 10A-H2B-mCherry | Alpelisib | 1 | 2.90 | 770.96 | 941 | 886 | 1.0614 | 1.8391 |
| MCF 10A-H2B-mCherry | Vorinostat | 5.6234 | 16.40 | 770.96 | 943 | 1625 | 0.5814 | 0.2081 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 2.90 | 770.96 | 943 | 886 | 1.0662 | 2.3433 |
| MCF 10A-H2B-mCherry | Etoposide | 1 | 7.30 | 770.96 | 944 | 1067 | 0.8847 | 0.5559 |
| MCF 10A-H2B-mCherry | Taxol | 0.00033333 | 5.10 | 770.96 | 945 | 984 | 0.9601 | 0.7825 |
| MCF 10A-H2B-mCherry | Etoposide | 0.018333 | 2.90 | 770.96 | 945 | 886 | 1.0660 | 1.7645 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.1 | 5.10 | 770.96 | 946 | 984 | 0.9618 | 0.8315 |
| MCF 10A-H2B-mCherry | Taxol | 0.0018 | 2.90 | 770.96 | 947 | 886 | 1.0682 | 1.8211 |
| MCF 10A-H2B-mCherry | Dasatinib | 1.7783 | 5.10 | 770.96 | 949 | 984 | 0.9630 | 0.8024 |
| MCF 10A-H2B-mCherry | Vorinostat | 3.1623 | 69.70 | 770.96 | 950 | 10312 | 0.0922 | 0.0572 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 2.90 | 770.96 | 950 | 886 | 1.0720 | 1.8576 |
| MCF 10A-H2B-mCherry | Alpelisib | 10 | 5.10 | 770.96 | 950 | 984 | 0.9657 | 0.8613 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.56234 | 2.90 | 770.96 | 950 | 886 | 1.0739 | 2.1723 |
| MCF 10A-H2B-mCherry | Taxol | 0.0056234 | 69.70 | 770.96 | 951 | 10312 | 0.0922 | 0.0556 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.0010833 | 2.90 | 770.96 | 951 | 886 | 1.0731 | 1.8915 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 2.90 | 770.96 | 951 | 886 | 1.0723 | 1.9578 |
| MCF 10A-H2B-mCherry | Palbociclib | 10 | 2.90 | 770.96 | 953 | 886 | 1.0766 | 2.3291 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 5.10 | 770.96 | 956 | 984 | 0.9733 | 0.9974 |
| MCF 10A-H2B-mCherry | Neratinib | 0.1 | 5.10 | 770.96 | 956 | 984 | 0.9711 | 0.8508 |
| MCF 10A-H2B-mCherry | Neratinib | 0.018 | 5.10 | 770.96 | 957 | 984 | 0.9746 | 0.9178 |