LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 4 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 1. - Dataset (ID:20312)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Vorinostat | 0.01 | 83.10 | 770.96 | 12591 | 12002 | 1.0492 | 1.0229 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.01 | 83.10 | 770.96 | 12648 | 12002 | 1.0536 | 1.0240 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.0010833 | 87.50 | 770.96 | 12782 | 12567 | 1.0173 | 1.0029 |
| MCF 10A-H2B-mCherry | Etoposide | 0.0010833 | 87.50 | 770.96 | 12792 | 12567 | 1.0179 | 1.0085 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 76.40 | 770.96 | 12798 | 11184 | 1.1440 | 1.0702 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.031667 | 87.50 | 770.96 | 12815 | 12567 | 1.0198 | 1.0090 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 85.30 | 770.96 | 12831 | 12277 | 1.0451 | 1.0198 |
| MCF 10A-H2B-mCherry | Neratinib | 0.0053333 | 85.30 | 770.96 | 12859 | 12277 | 1.0474 | 1.0233 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.0033333 | 85.30 | 770.96 | 12875 | 12277 | 1.0488 | 1.0239 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.01 | 85.30 | 770.96 | 12913 | 12277 | 1.0518 | 1.0225 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.17783 | 85.30 | 770.96 | 12919 | 12277 | 1.0523 | 1.0230 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.01 | 85.30 | 770.96 | 12923 | 12277 | 1.0527 | 1.0244 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 78.60 | 770.96 | 13132 | 11443 | 1.1473 | 1.0711 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.01 | 87.50 | 770.96 | 13180 | 12567 | 1.0486 | 1.0220 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.17783 | 87.50 | 770.96 | 13204 | 12567 | 1.0506 | 1.0218 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 87.50 | 770.96 | 13209 | 12567 | 1.0511 | 1.0222 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.01 | 87.50 | 770.96 | 13230 | 12567 | 1.0529 | 1.0226 |
| MCF 10A-H2B-mCherry | Neratinib | 0.0053333 | 87.50 | 770.96 | 13241 | 12567 | 1.0536 | 1.0261 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.0033333 | 87.50 | 770.96 | 13271 | 12567 | 1.0559 | 1.0271 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 80.80 | 770.96 | 13502 | 11725 | 1.1513 | 1.0723 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 83.10 | 770.96 | 13822 | 12002 | 1.1514 | 1.0717 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 85.30 | 770.96 | 14218 | 12277 | 1.1580 | 1.0740 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 87.50 | 770.96 | 14521 | 12567 | 1.1556 | 1.0723 |