LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 4 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 1. - Dataset (ID:20312)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Vorinostat | 0.17783 | 80.80 | 770.96 | 12121 | 11725 | 1.0338 | 1.0145 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 71.90 | 770.96 | 12125 | 10631 | 1.1400 | 1.0696 |
| MCF 10A-H2B-mCherry | 0 | 87.50 | 770.96 | 12125 | 12567 | 0.9648 | 0.9748 | |
| MCF 10A-H2B-mCherry | Alpelisib | 0.031667 | 83.10 | 770.96 | 12162 | 12002 | 1.0132 | 1.0060 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 87.50 | 770.96 | 12164 | 12567 | 0.9679 | 0.9791 |
| MCF 10A-H2B-mCherry | Taxol | 0.00053333 | 87.50 | 770.96 | 12168 | 12567 | 0.9684 | 0.9791 |
| MCF 10A-H2B-mCherry | Etoposide | 0.031667 | 87.50 | 770.96 | 12169 | 12567 | 0.9685 | 0.9814 |
| MCF 10A-H2B-mCherry | Neratinib | 0.0013333 | 85.30 | 770.96 | 12229 | 12277 | 0.9962 | 0.9939 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.0033333 | 80.80 | 770.96 | 12258 | 11725 | 1.0455 | 1.0227 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.1 | 87.50 | 770.96 | 12268 | 12567 | 0.9763 | 0.9866 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 87.50 | 770.96 | 12270 | 12567 | 0.9765 | 0.9843 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 80.80 | 770.96 | 12288 | 11725 | 1.0479 | 1.0222 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.0010833 | 83.10 | 770.96 | 12325 | 12002 | 1.0267 | 1.0092 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.01 | 80.80 | 770.96 | 12331 | 11725 | 1.0513 | 1.0234 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.0010833 | 87.50 | 770.96 | 12367 | 12567 | 0.9841 | 0.9917 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.01 | 80.80 | 770.96 | 12377 | 11725 | 1.0558 | 1.0265 |
| MCF 10A-H2B-mCherry | Etoposide | 0.0010833 | 85.30 | 770.96 | 12394 | 12277 | 1.0096 | 1.0044 |
| MCF 10A-H2B-mCherry | Neratinib | 0.0013333 | 87.50 | 770.96 | 12452 | 12567 | 0.9905 | 0.9908 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.17783 | 83.10 | 770.96 | 12453 | 12002 | 1.0375 | 1.0161 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 74.10 | 770.96 | 12481 | 10921 | 1.1425 | 1.0701 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.031667 | 85.30 | 770.96 | 12496 | 12277 | 1.0179 | 1.0082 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.0033333 | 83.10 | 770.96 | 12536 | 12002 | 1.0444 | 1.0219 |
| MCF 10A-H2B-mCherry | Neratinib | 0.0053333 | 83.10 | 770.96 | 12537 | 12002 | 1.0445 | 1.0221 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.0010833 | 85.30 | 770.96 | 12548 | 12277 | 1.0220 | 1.0061 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 83.10 | 770.96 | 12569 | 12002 | 1.0471 | 1.0213 |