LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 4 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 1. - Dataset (ID:20312)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Alpelisib | 0.0033333 | 71.90 | 770.96 | 10368 | 10631 | 0.9750 | 0.9850 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.0010833 | 67.50 | 770.96 | 10380 | 9939 | 1.0438 | 1.0215 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 67.50 | 770.96 | 10383 | 9939 | 1.0452 | 1.0228 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.01 | 85.30 | 770.96 | 10384 | 12277 | 0.8458 | 0.9148 |
| MCF 10A-H2B-mCherry | Neratinib | 0.0033333 | 71.90 | 770.96 | 10384 | 10631 | 0.9767 | 0.9875 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.31623 | 83.10 | 770.96 | 10386 | 12002 | 0.8653 | 0.9280 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 78.60 | 770.96 | 10389 | 11443 | 0.9077 | 0.9503 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 83.10 | 770.96 | 10395 | 12002 | 0.8661 | 0.9271 |
| MCF 10A-H2B-mCherry | Taxol | 0.00013333 | 74.10 | 770.96 | 10399 | 10921 | 0.9519 | 0.9733 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.56234 | 78.60 | 770.96 | 10401 | 11443 | 0.9090 | 0.9480 |
| MCF 10A-H2B-mCherry | Neratinib | 0.018 | 87.50 | 770.96 | 10402 | 12567 | 0.8279 | 0.9046 |
| MCF 10A-H2B-mCherry | Neratinib | 0.0053333 | 69.70 | 770.96 | 10406 | 10312 | 1.0091 | 1.0047 |
| MCF 10A-H2B-mCherry | Etoposide | 0.031667 | 74.10 | 770.96 | 10413 | 10921 | 0.9530 | 0.9735 |
| MCF 10A-H2B-mCherry | Neratinib | 0.01 | 76.40 | 770.96 | 10427 | 11184 | 0.9323 | 0.9613 |
| MCF 10A-H2B-mCherry | Taxol | 0.00033333 | 74.10 | 770.96 | 10438 | 10921 | 0.9554 | 0.9752 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 63.00 | 770.96 | 10441 | 9152 | 1.1399 | 1.0736 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.01 | 85.30 | 770.96 | 10454 | 12277 | 0.8515 | 0.9193 |
| MCF 10A-H2B-mCherry | Etoposide | 0.01 | 76.40 | 770.96 | 10455 | 11184 | 0.9343 | 0.9636 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 74.10 | 770.96 | 10460 | 10921 | 0.9581 | 0.9758 |
| MCF 10A-H2B-mCherry | Etoposide | 0.1 | 87.50 | 770.96 | 10463 | 12567 | 0.8325 | 0.9087 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.018333 | 80.80 | 770.96 | 10477 | 11725 | 0.8932 | 0.9405 |
| MCF 10A-H2B-mCherry | Etoposide | 0.0010833 | 71.90 | 770.96 | 10481 | 10631 | 0.9858 | 0.9921 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.0033333 | 80.80 | 770.96 | 10496 | 11725 | 0.8955 | 0.9380 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.17783 | 71.90 | 770.96 | 10501 | 10631 | 0.9875 | 0.9915 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.01 | 87.50 | 770.96 | 10506 | 12567 | 0.8362 | 0.9092 |