LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 4 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 1. - Dataset (ID:20312)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Etoposide | 10 | 9.60 | 770.96 | 818 | 1178 | 0.6961 | 0.1139 |
| MCF 10A-H2B-mCherry | Etoposide | 1 | 2.90 | 770.96 | 819 | 886 | 0.9244 | 0.4377 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 18.60 | 770.96 | 819 | 1786 | 0.4594 | 0.0524 |
| MCF 10A-H2B-mCherry | Taxol | 0.01 | 27.50 | 770.96 | 819 | 2754 | 0.2982 | 0.0279 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 5.10 | 770.96 | 820 | 984 | 0.8354 | 0.2482 |
| MCF 10A-H2B-mCherry | Dasatinib | 10 | 76.40 | 770.96 | 820 | 11184 | 0.0734 | 0.0137 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 11.90 | 770.96 | 820 | 1319 | 0.6232 | 0.0891 |
| MCF 10A-H2B-mCherry | Dasatinib | 10 | 2.90 | 770.96 | 820 | 886 | 0.9269 | 0.5745 |
| MCF 10A-H2B-mCherry | Taxol | 0.01 | 9.60 | 770.96 | 821 | 1178 | 0.6981 | 0.1168 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 20.80 | 770.96 | 821 | 1959 | 0.4200 | 0.0489 |
| MCF 10A-H2B-mCherry | Vorinostat | 5.6234 | 31.90 | 770.96 | 821 | 3294 | 0.2499 | 0.0307 |
| MCF 10A-H2B-mCherry | Etoposide | 0.0010833 | 2.90 | 770.96 | 822 | 886 | 0.9273 | 0.3891 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 14.10 | 770.96 | 824 | 1478 | 0.5579 | 0.0750 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 2.90 | 770.96 | 825 | 886 | 0.9324 | 0.6295 |
| MCF 10A-H2B-mCherry | Vorinostat | 10 | 18.60 | 770.96 | 825 | 1786 | 0.4619 | 0.0548 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 25.30 | 770.96 | 826 | 2456 | 0.3368 | 0.0421 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 23.00 | 770.96 | 826 | 2193 | 0.3773 | 0.0472 |
| MCF 10A-H2B-mCherry | Etoposide | 3.1623 | 2.90 | 770.96 | 827 | 886 | 0.9325 | 0.4213 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 36.40 | 770.96 | 827 | 3985 | 0.2079 | 0.0298 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 60.80 | 770.96 | 828 | 8711 | 0.0952 | 0.0206 |
| MCF 10A-H2B-mCherry | Taxol | 0.0056234 | 85.30 | 770.96 | 828 | 12277 | 0.0674 | 0.0176 |
| MCF 10A-H2B-mCherry | Alpelisib | 3.1623 | 2.90 | 770.96 | 829 | 886 | 0.9376 | 0.6950 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 38.60 | 770.96 | 832 | 4421 | 0.1886 | 0.0304 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 2.90 | 770.96 | 833 | 886 | 0.9423 | 0.7318 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.031667 | 2.90 | 770.96 | 833 | 886 | 0.9413 | 0.5073 |