LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 4 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 1. - Dataset (ID:20312)
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Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|
MCF 10A-H2B-mCherry | Taxol | 0.01 | 29.70 | 770.96 | 748 | 3022 | 0.2482 | -0.0228 |
MCF 10A-H2B-mCherry | Vorinostat | 10 | 25.30 | 770.96 | 749 | 2456 | 0.3051 | -0.0221 |
MCF 10A-H2B-mCherry | Vorinostat | 5.6234 | 49.70 | 770.96 | 751 | 6511 | 0.1155 | -0.0085 |
MCF 10A-H2B-mCherry | Vorinostat | 5.6234 | 47.50 | 770.96 | 754 | 6082 | 0.1242 | -0.0074 |
MCF 10A-H2B-mCherry | Taxol | 0.31623 | 5.10 | 770.96 | 755 | 984 | 0.7669 | -0.0373 |
MCF 10A-H2B-mCherry | Vorinostat | 5.6234 | 58.60 | 770.96 | 756 | 8264 | 0.0916 | -0.0057 |
MCF 10A-H2B-mCherry | Vorinostat | 5.6234 | 85.30 | 770.96 | 761 | 12277 | 0.0620 | -0.0035 |
MCF 10A-H2B-mCherry | Taxol | 0.01 | 7.30 | 770.96 | 763 | 1067 | 0.7160 | -0.0069 |
MCF 10A-H2B-mCherry | Dasatinib | 10 | 80.80 | 770.96 | 767 | 11725 | 0.0655 | -0.0045 |
MCF 10A-H2B-mCherry | Vorinostat | 10 | 23.00 | 770.96 | 772 | 2193 | 0.3524 | -0.0032 |
MCF 10A-H2B-mCherry | Taxol | 0.31623 | 2.90 | 770.96 | 772 | 886 | 0.8712 | 0.1097 |
MCF 10A-H2B-mCherry | Etoposide | 10 | 87.50 | 770.96 | 773 | 12567 | 0.0615 | 0.0006 |
MCF 10A-H2B-mCherry | Etoposide | 10 | 85.30 | 770.96 | 775 | 12277 | 0.0631 | 0.0008 |
MCF 10A-H2B-mCherry | Vorinostat | 5.6234 | 45.30 | 770.96 | 776 | 5677 | 0.1368 | 0.0020 |
MCF 10A-H2B-mCherry | Taxol | 0.031623 | 7.30 | 770.96 | 783 | 1067 | 0.7344 | 0.0404 |
MCF 10A-H2B-mCherry | Vorinostat | 5.6234 | 43.00 | 770.96 | 783 | 5280 | 0.1486 | 0.0057 |
MCF 10A-H2B-mCherry | Etoposide | 10 | 69.70 | 770.96 | 783 | 10312 | 0.0760 | 0.0040 |
MCF 10A-H2B-mCherry | Etoposide | 10 | 83.10 | 770.96 | 784 | 12002 | 0.0654 | 0.0041 |
MCF 10A-H2B-mCherry | Etoposide | 10 | 80.80 | 770.96 | 784 | 11725 | 0.0669 | 0.0042 |
MCF 10A-H2B-mCherry | Taxol | 0.031623 | 5.10 | 770.96 | 787 | 984 | 0.7997 | 0.0741 |
MCF 10A-H2B-mCherry | Dasatinib | 3.1623 | 2.90 | 770.96 | 787 | 886 | 0.8886 | 0.1379 |
MCF 10A-H2B-mCherry | Dasatinib | 10 | 78.60 | 770.96 | 787 | 11443 | 0.0689 | 0.0028 |
MCF 10A-H2B-mCherry | Vorinostat | 10 | 20.80 | 770.96 | 790 | 1959 | 0.4036 | 0.0150 |
MCF 10A-H2B-mCherry | Dasatinib | 0.31623 | 2.90 | 770.96 | 790 | 886 | 0.8930 | 0.2137 |
MCF 10A-H2B-mCherry | Etoposide | 10 | 71.90 | 770.96 | 794 | 10631 | 0.0747 | 0.0077 |