LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 4 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 1. - Dataset (ID:20312)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Vorinostat | 3.1623 | 87.50 | 770.96 | 1065 | 12567 | 0.0848 | 0.0830 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.0033333 | 87.50 | 770.96 | 11987 | 12567 | 0.9539 | 0.9736 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 87.50 | 770.96 | 8436 | 12567 | 0.6715 | 0.8022 |
| MCF 10A-H2B-mCherry | Etoposide | 1.7783 | 87.50 | 770.96 | 1271 | 12567 | 0.1012 | 0.1315 |
| MCF 10A-H2B-mCherry | Etoposide | 0.56234 | 87.50 | 770.96 | 3049 | 12567 | 0.2428 | 0.3947 |
| MCF 10A-H2B-mCherry | Alpelisib | 3.1623 | 87.50 | 770.96 | 10049 | 12567 | 0.7997 | 0.8902 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.0010833 | 87.50 | 770.96 | 12782 | 12567 | 1.0173 | 1.0029 |
| MCF 10A-H2B-mCherry | Taxol | 0.0002 | 87.50 | 770.96 | 11864 | 12567 | 0.9441 | 0.9686 |
| MCF 10A-H2B-mCherry | Neratinib | 0.0013333 | 87.50 | 770.96 | 12452 | 12567 | 0.9905 | 0.9908 |
| MCF 10A-H2B-mCherry | Palbociclib | 1.7783 | 87.50 | 770.96 | 2242 | 12567 | 0.1785 | 0.3011 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 87.50 | 770.96 | 4331 | 12567 | 0.3446 | 0.5322 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 87.50 | 770.96 | 1618 | 12567 | 0.1288 | 0.2016 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.01 | 87.50 | 770.96 | 13180 | 12567 | 1.0486 | 1.0220 |
| MCF 10A-H2B-mCherry | Alpelisib | 10 | 87.50 | 770.96 | 6863 | 12567 | 0.5462 | 0.7163 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 87.50 | 770.96 | 14521 | 12567 | 1.1556 | 1.0723 |
| MCF 10A-H2B-mCherry | Taxol | 0.1 | 87.50 | 770.96 | 88 | 12567 | 0.0070 | -0.4271 |
| MCF 10A-H2B-mCherry | Dasatinib | 10 | 87.50 | 770.96 | 691 | 12567 | 0.0550 | -0.0306 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.17783 | 87.50 | 770.96 | 6652 | 12567 | 0.5292 | 0.7054 |
| MCF 10A-H2B-mCherry | Neratinib | 0.031623 | 87.50 | 770.96 | 9959 | 12567 | 0.7928 | 0.8626 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.1 | 87.50 | 770.96 | 8191 | 12567 | 0.6519 | 0.7943 |
| MCF 10A-H2B-mCherry | Neratinib | 0.0033333 | 87.50 | 770.96 | 11788 | 12567 | 0.9381 | 0.9670 |
| MCF 10A-H2B-mCherry | Palbociclib | 1 | 87.50 | 770.96 | 3550 | 12567 | 0.2826 | 0.4575 |
| MCF 10A-H2B-mCherry | Taxol | 0.0018 | 87.50 | 770.96 | 5984 | 12567 | 0.4763 | 0.6597 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 87.50 | 770.96 | 3073 | 12567 | 0.2445 | 0.4089 |
| MCF 10A-H2B-mCherry | Etoposide | 0.056667 | 87.50 | 770.96 | 11441 | 12567 | 0.9102 | 0.9466 |