LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 4 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 1. - Dataset (ID:20312)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Etoposide | 0.31623 | 7.30 | 770.96 | 1061 | 1067 | 0.9961 | 1.0377 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.01 | 7.30 | 770.96 | 1110 | 1067 | 1.0382 | 1.1574 |
| MCF 10A-H2B-mCherry | Palbociclib | 3.1623 | 7.30 | 770.96 | 1069 | 1067 | 1.0010 | 1.0004 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 7.30 | 770.96 | 1141 | 1067 | 1.0715 | 1.3914 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 7.30 | 770.96 | 1100 | 1067 | 1.0317 | 1.1690 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.1 | 7.30 | 770.96 | 1108 | 1067 | 1.0380 | 1.1652 |
| MCF 10A-H2B-mCherry | Taxol | 0.31623 | 7.30 | 770.96 | 727 | 1067 | 0.6815 | -0.1095 |
| MCF 10A-H2B-mCherry | Etoposide | 0.031667 | 7.30 | 770.96 | 1078 | 1067 | 1.0101 | 1.0447 |
| MCF 10A-H2B-mCherry | Palbociclib | 1.7783 | 7.30 | 770.96 | 962 | 1067 | 0.9030 | 0.6359 |
| MCF 10A-H2B-mCherry | Taxol | 0.1 | 7.30 | 770.96 | 678 | 1067 | 0.6363 | -0.2337 |
| MCF 10A-H2B-mCherry | Taxol | 0.031623 | 7.30 | 770.96 | 783 | 1067 | 0.7344 | 0.0404 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 7.30 | 770.96 | 1058 | 1067 | 0.9896 | 0.9699 |
| MCF 10A-H2B-mCherry | Neratinib | 0.56234 | 7.30 | 770.96 | 1146 | 1067 | 1.0747 | 1.3639 |
| MCF 10A-H2B-mCherry | Etoposide | 3.1623 | 7.30 | 770.96 | 858 | 1067 | 0.8028 | 0.2555 |
| MCF 10A-H2B-mCherry | Dasatinib | 10 | 7.30 | 770.96 | 919 | 1067 | 0.8633 | 0.4949 |
| MCF 10A-H2B-mCherry | Neratinib | 0.01 | 7.30 | 770.96 | 1069 | 1067 | 1.0007 | 0.9979 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.31623 | 7.30 | 770.96 | 987 | 1067 | 0.9258 | 0.7193 |
| MCF 10A-H2B-mCherry | Palbociclib | 1 | 7.30 | 770.96 | 1074 | 1067 | 1.0063 | 1.0295 |
| MCF 10A-H2B-mCherry | Etoposide | 0.0033333 | 7.30 | 770.96 | 1089 | 1067 | 1.0200 | 1.0860 |
| MCF 10A-H2B-mCherry | Neratinib | 0.31623 | 7.30 | 770.96 | 1025 | 1067 | 0.9620 | 0.8787 |
| MCF 10A-H2B-mCherry | Dasatinib | 1.7783 | 7.30 | 770.96 | 1044 | 1067 | 0.9778 | 0.9119 |
| MCF 10A-H2B-mCherry | Taxol | 0.01 | 7.30 | 770.96 | 763 | 1067 | 0.7160 | -0.0069 |
| MCF 10A-H2B-mCherry | Neratinib | 0.0053333 | 7.30 | 770.96 | 1029 | 1067 | 0.9641 | 0.8661 |
| MCF 10A-H2B-mCherry | Etoposide | 1.7783 | 7.30 | 770.96 | 986 | 1067 | 0.9258 | 0.7325 |
| MCF 10A-H2B-mCherry | Etoposide | 0.056667 | 7.30 | 770.96 | 1072 | 1067 | 1.0061 | 1.0667 |