LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 4 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 1. - Dataset (ID:20312)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Palbociclib | 1.7783 | 7.30 | 770.96 | 962 | 1067 | 0.9030 | 0.6359 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.1 | 7.30 | 770.96 | 1013 | 1067 | 0.9493 | 0.8028 |
| MCF 10A-H2B-mCherry | Neratinib | 0.0033333 | 7.30 | 770.96 | 1140 | 1067 | 1.0700 | 1.3675 |
| MCF 10A-H2B-mCherry | Etoposide | 0.0033333 | 7.30 | 770.96 | 1089 | 1067 | 1.0200 | 1.0860 |
| MCF 10A-H2B-mCherry | Etoposide | 0.1 | 7.30 | 770.96 | 1061 | 1067 | 0.9957 | 1.0182 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 7.30 | 770.96 | 1062 | 1067 | 0.9955 | 0.9819 |
| MCF 10A-H2B-mCherry | Taxol | 0.1 | 7.30 | 770.96 | 678 | 1067 | 0.6363 | -0.2337 |
| MCF 10A-H2B-mCherry | Etoposide | 1 | 7.30 | 770.96 | 944 | 1067 | 0.8847 | 0.5559 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.31623 | 7.30 | 770.96 | 967 | 1067 | 0.9068 | 0.6269 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.0033333 | 7.30 | 770.96 | 1044 | 1067 | 0.9793 | 0.9354 |
| MCF 10A-H2B-mCherry | Neratinib | 0.17783 | 7.30 | 770.96 | 1065 | 1067 | 0.9987 | 1.0239 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.31623 | 7.30 | 770.96 | 987 | 1067 | 0.9258 | 0.7193 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.17783 | 7.30 | 770.96 | 1095 | 1067 | 1.0259 | 1.1242 |
| MCF 10A-H2B-mCherry | Taxol | 0.031623 | 7.30 | 770.96 | 783 | 1067 | 0.7344 | 0.0404 |
| MCF 10A-H2B-mCherry | Neratinib | 0.1 | 7.30 | 770.96 | 1016 | 1067 | 0.9516 | 0.8007 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.0010833 | 7.30 | 770.96 | 1147 | 1067 | 1.0744 | 1.3347 |
| MCF 10A-H2B-mCherry | Taxol | 0.01 | 7.30 | 770.96 | 763 | 1067 | 0.7160 | -0.0069 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 7.30 | 770.96 | 1050 | 1067 | 0.9848 | 0.9557 |
| MCF 10A-H2B-mCherry | Neratinib | 0.056234 | 7.30 | 770.96 | 1071 | 1067 | 1.0056 | 1.0754 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.0033333 | 7.30 | 770.96 | 1072 | 1067 | 1.0042 | 1.0622 |
| MCF 10A-H2B-mCherry | Etoposide | 0.56234 | 7.30 | 770.96 | 1054 | 1067 | 0.9876 | 0.9485 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.1 | 7.30 | 770.96 | 1047 | 1067 | 0.9816 | 0.9493 |
| MCF 10A-H2B-mCherry | Taxol | 0.017783 | 7.30 | 770.96 | 669 | 1067 | 0.6270 | -0.2570 |
| MCF 10A-H2B-mCherry | 0 | 7.30 | 770.96 | 1070 | 1067 | 1.0026 | 1.0274 | |
| MCF 10A-H2B-mCherry | Neratinib | 0.0013333 | 7.30 | 770.96 | 1107 | 1067 | 1.0382 | 1.2038 |