LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 4 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 1. - Dataset (ID:20312)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Taxol | 0.00033333 | 34.10 | 770.96 | 3459 | 3605 | 0.9588 | 0.9618 |
| MCF 10A-H2B-mCherry | Taxol | 0.00033333 | 31.90 | 770.96 | 3173 | 3294 | 0.9627 | 0.9635 |
| MCF 10A-H2B-mCherry | Taxol | 0.00033333 | 36.40 | 770.96 | 3835 | 3985 | 0.9615 | 0.9664 |
| MCF 10A-H2B-mCherry | Taxol | 0.00033333 | 29.70 | 770.96 | 2921 | 3022 | 0.9659 | 0.9644 |
| MCF 10A-H2B-mCherry | Taxol | 0.00033333 | 38.60 | 770.96 | 4263 | 4421 | 0.9634 | 0.9699 |
| MCF 10A-H2B-mCherry | Taxol | 0.00033333 | 54.10 | 770.96 | 7114 | 7405 | 0.9600 | 0.9746 |
| MCF 10A-H2B-mCherry | Taxol | 0.00033333 | 69.70 | 770.96 | 9897 | 10312 | 0.9591 | 0.9769 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 18.60 | 770.96 | 1930 | 1786 | 1.0834 | 1.1404 |
| MCF 10A-H2B-mCherry | Taxol | 0.00033333 | 25.30 | 770.96 | 2372 | 2456 | 0.9656 | 0.9579 |
| MCF 10A-H2B-mCherry | Taxol | 0.00033333 | 23.00 | 770.96 | 2083 | 2193 | 0.9498 | 0.9321 |
| MCF 10A-H2B-mCherry | Taxol | 0.00033333 | 27.50 | 770.96 | 2645 | 2754 | 0.9601 | 0.9557 |
| MCF 10A-H2B-mCherry | Taxol | 0.00033333 | 71.90 | 770.96 | 10199 | 10631 | 0.9587 | 0.9768 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 20.80 | 770.96 | 2100 | 1959 | 1.0746 | 1.1114 |
| MCF 10A-H2B-mCherry | Taxol | 0.00033333 | 11.90 | 770.96 | 1270 | 1319 | 0.9631 | 0.9063 |
| MCF 10A-H2B-mCherry | Taxol | 0.00033333 | 14.10 | 770.96 | 1431 | 1478 | 0.9682 | 0.9317 |
| MCF 10A-H2B-mCherry | Taxol | 0.00033333 | 16.40 | 770.96 | 1572 | 1625 | 0.9678 | 0.9397 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 11.90 | 770.96 | 1402 | 1319 | 1.0663 | 1.1957 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 9.60 | 770.96 | 1255 | 1178 | 1.0693 | 1.2830 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 7.30 | 770.96 | 1141 | 1067 | 1.0715 | 1.3914 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 5.10 | 770.96 | 1051 | 984 | 1.0711 | 1.6265 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 2.90 | 770.96 | 943 | 886 | 1.0662 | 2.3433 |
| MCF 10A-H2B-mCherry | Taxol | 0.00033333 | 18.60 | 770.96 | 1741 | 1786 | 0.9744 | 0.9578 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 23.00 | 770.96 | 2316 | 2193 | 1.0587 | 1.0769 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 83.10 | 770.96 | 11292 | 12002 | 0.9409 | 0.9660 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 74.10 | 770.96 | 10460 | 10921 | 0.9581 | 0.9758 |