LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 4 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 1. - Dataset (ID:20312)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Taxol | 0.01 | 43.00 | 770.96 | 617 | 5280 | 0.1177 | -0.0833 |
| MCF 10A-H2B-mCherry | Taxol | 0.0056234 | 60.80 | 770.96 | 1029 | 8711 | 0.1181 | 0.0807 |
| MCF 10A-H2B-mCherry | Etoposide | 1.7783 | 71.90 | 770.96 | 1259 | 10631 | 0.1185 | 0.1374 |
| MCF 10A-H2B-mCherry | Palbociclib | 10 | 78.60 | 770.96 | 1355 | 11443 | 0.1185 | 0.1558 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 85.30 | 770.96 | 1463 | 12277 | 0.1192 | 0.1723 |
| MCF 10A-H2B-mCherry | Vorinostat | 3.1623 | 54.10 | 770.96 | 882 | 7405 | 0.1192 | 0.0414 |
| MCF 10A-H2B-mCherry | Taxol | 0.017783 | 29.70 | 770.96 | 361 | 3022 | 0.1200 | -0.3326 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 69.70 | 770.96 | 1241 | 10312 | 0.1202 | 0.1299 |
| MCF 10A-H2B-mCherry | Palbociclib | 10 | 76.40 | 770.96 | 1346 | 11184 | 0.1204 | 0.1554 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 83.10 | 770.96 | 1449 | 12002 | 0.1208 | 0.1709 |
| MCF 10A-H2B-mCherry | Etoposide | 1.7783 | 69.70 | 770.96 | 1254 | 10312 | 0.1217 | 0.1381 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 67.50 | 770.96 | 1216 | 9939 | 0.1221 | 0.1254 |
| MCF 10A-H2B-mCherry | Palbociclib | 10 | 74.10 | 770.96 | 1343 | 10921 | 0.1230 | 0.1562 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 58.60 | 770.96 | 1019 | 8264 | 0.1233 | 0.0832 |
| MCF 10A-H2B-mCherry | Dasatinib | 10 | 56.40 | 770.96 | 968 | 7845 | 0.1237 | 0.0690 |
| MCF 10A-H2B-mCherry | Vorinostat | 5.6234 | 47.50 | 770.96 | 754 | 6082 | 0.1242 | -0.0074 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 65.30 | 770.96 | 1193 | 9591 | 0.1242 | 0.1231 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 49.70 | 770.96 | 809 | 6511 | 0.1244 | 0.0158 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 80.80 | 770.96 | 1459 | 11725 | 0.1245 | 0.1745 |
| MCF 10A-H2B-mCherry | Etoposide | 3.1623 | 51.90 | 770.96 | 871 | 6944 | 0.1253 | 0.0379 |
| MCF 10A-H2B-mCherry | Vorinostat | 10 | 43.00 | 770.96 | 661 | 5280 | 0.1253 | -0.0574 |
| MCF 10A-H2B-mCherry | Palbociclib | 10 | 71.90 | 770.96 | 1334 | 10631 | 0.1255 | 0.1560 |
| MCF 10A-H2B-mCherry | Taxol | 0.031623 | 31.90 | 770.96 | 411 | 3294 | 0.1256 | -0.2686 |
| MCF 10A-H2B-mCherry | Vorinostat | 3.1623 | 51.90 | 770.96 | 875 | 6944 | 0.1261 | 0.0402 |
| MCF 10A-H2B-mCherry | Palbociclib | 5.6234 | 87.50 | 770.96 | 1589 | 12567 | 0.1265 | 0.1925 |