LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 4 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 1. - Dataset (ID:20312)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Taxol | 0.31623 | 23.00 | 770.96 | 239 | 2193 | 0.1089 | -0.5419 |
| MCF 10A-H2B-mCherry | Etoposide | 1.7783 | 80.80 | 770.96 | 1282 | 11725 | 0.1094 | 0.1377 |
| MCF 10A-H2B-mCherry | Vorinostat | 3.1623 | 58.60 | 770.96 | 904 | 8264 | 0.1094 | 0.0470 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 54.10 | 770.96 | 816 | 7405 | 0.1104 | 0.0172 |
| MCF 10A-H2B-mCherry | Etoposide | 3.1623 | 56.40 | 770.96 | 872 | 7845 | 0.1110 | 0.0362 |
| MCF 10A-H2B-mCherry | Palbociclib | 10 | 83.10 | 770.96 | 1344 | 12002 | 0.1120 | 0.1505 |
| MCF 10A-H2B-mCherry | Etoposide | 1.7783 | 78.60 | 770.96 | 1283 | 11443 | 0.1122 | 0.1390 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 87.50 | 770.96 | 1411 | 12567 | 0.1123 | 0.1486 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 74.10 | 770.96 | 1230 | 10921 | 0.1125 | 0.1209 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 78.60 | 770.96 | 1294 | 11443 | 0.1130 | 0.1310 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 60.80 | 770.96 | 984 | 8711 | 0.1130 | 0.0711 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 83.10 | 770.96 | 1357 | 12002 | 0.1130 | 0.1421 |
| MCF 10A-H2B-mCherry | Vorinostat | 3.1623 | 56.40 | 770.96 | 894 | 7845 | 0.1141 | 0.0447 |
| MCF 10A-H2B-mCherry | Vorinostat | 10 | 45.30 | 770.96 | 649 | 5677 | 0.1143 | -0.0618 |
| MCF 10A-H2B-mCherry | Palbociclib | 10 | 80.80 | 770.96 | 1341 | 11725 | 0.1144 | 0.1511 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 71.90 | 770.96 | 1217 | 10631 | 0.1144 | 0.1215 |
| MCF 10A-H2B-mCherry | Etoposide | 1.7783 | 76.40 | 770.96 | 1279 | 11184 | 0.1145 | 0.1394 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 80.80 | 770.96 | 1345 | 11725 | 0.1147 | 0.1403 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 85.30 | 770.96 | 1411 | 12277 | 0.1150 | 0.1492 |
| MCF 10A-H2B-mCherry | Vorinostat | 5.6234 | 49.70 | 770.96 | 751 | 6511 | 0.1155 | -0.0085 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 87.50 | 770.96 | 1454 | 12567 | 0.1157 | 0.1688 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 51.90 | 770.96 | 807 | 6944 | 0.1164 | 0.0146 |
| MCF 10A-H2B-mCherry | Etoposide | 1.7783 | 74.10 | 770.96 | 1271 | 10921 | 0.1164 | 0.1389 |
| MCF 10A-H2B-mCherry | Dasatinib | 10 | 58.60 | 770.96 | 959 | 8264 | 0.1164 | 0.0642 |
| MCF 10A-H2B-mCherry | Etoposide | 3.1623 | 54.10 | 770.96 | 870 | 7405 | 0.1174 | 0.0366 |