LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 4 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 1. - Dataset (ID:20312)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Taxol | 0.017783 | 31.90 | 770.96 | 319 | 3294 | 0.0972 | -0.3577 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 58.60 | 770.96 | 804 | 8264 | 0.0974 | 0.0123 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 65.30 | 770.96 | 939 | 9591 | 0.0978 | 0.0514 |
| MCF 10A-H2B-mCherry | Taxol | 0.1 | 25.30 | 770.96 | 241 | 2456 | 0.0983 | -0.5061 |
| MCF 10A-H2B-mCherry | Vorinostat | 3.1623 | 63.00 | 770.96 | 909 | 9152 | 0.0994 | 0.0471 |
| MCF 10A-H2B-mCherry | Vorinostat | 5.6234 | 54.10 | 770.96 | 742 | 7405 | 0.1003 | -0.0118 |
| MCF 10A-H2B-mCherry | Etoposide | 3.1623 | 60.80 | 770.96 | 876 | 8711 | 0.1004 | 0.0358 |
| MCF 10A-H2B-mCherry | Etoposide | 1.7783 | 87.50 | 770.96 | 1271 | 12567 | 0.1012 | 0.1315 |
| MCF 10A-H2B-mCherry | Dasatinib | 10 | 63.00 | 770.96 | 925 | 9152 | 0.1014 | 0.0505 |
| MCF 10A-H2B-mCherry | Taxol | 0.031623 | 34.10 | 770.96 | 365 | 3605 | 0.1021 | -0.2980 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 56.40 | 770.96 | 804 | 7845 | 0.1026 | 0.0125 |
| MCF 10A-H2B-mCherry | Taxol | 0.0056234 | 65.30 | 770.96 | 990 | 9591 | 0.1032 | 0.0680 |
| MCF 10A-H2B-mCherry | Vorinostat | 3.1623 | 60.80 | 770.96 | 903 | 8711 | 0.1038 | 0.0458 |
| MCF 10A-H2B-mCherry | Taxol | 0.01 | 45.30 | 770.96 | 588 | 5677 | 0.1042 | -0.0950 |
| MCF 10A-H2B-mCherry | Etoposide | 1.7783 | 85.30 | 770.96 | 1284 | 12277 | 0.1047 | 0.1357 |
| MCF 10A-H2B-mCherry | Vorinostat | 10 | 47.50 | 770.96 | 637 | 6082 | 0.1048 | -0.0651 |
| MCF 10A-H2B-mCherry | Palbociclib | 10 | 87.50 | 770.96 | 1330 | 12567 | 0.1058 | 0.1444 |
| MCF 10A-H2B-mCherry | Vorinostat | 5.6234 | 51.90 | 770.96 | 740 | 6944 | 0.1067 | -0.0129 |
| MCF 10A-H2B-mCherry | Etoposide | 3.1623 | 58.60 | 770.96 | 883 | 8264 | 0.1067 | 0.0387 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 63.00 | 770.96 | 985 | 9152 | 0.1076 | 0.0682 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 76.40 | 770.96 | 1206 | 11184 | 0.1077 | 0.1160 |
| MCF 10A-H2B-mCherry | Dasatinib | 10 | 60.80 | 770.96 | 934 | 8711 | 0.1077 | 0.0547 |
| MCF 10A-H2B-mCherry | Taxol | 0.0056234 | 63.00 | 770.96 | 991 | 9152 | 0.1082 | 0.0688 |
| MCF 10A-H2B-mCherry | Palbociclib | 10 | 85.30 | 770.96 | 1328 | 12277 | 0.1082 | 0.1455 |
| MCF 10A-H2B-mCherry | Etoposide | 1.7783 | 83.10 | 770.96 | 1305 | 12002 | 0.1088 | 0.1415 |