LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 4 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 1. - Dataset (ID:20312)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 1 | 76.40 | 770.96 | 1464 | 11184 | 0.1311 | 0.1790 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 38.60 | 770.96 | 1178 | 4421 | 0.2660 | 0.1796 |
| MCF 10A-H2B-mCherry | Palbociclib | 10 | 56.40 | 770.96 | 1342 | 7845 | 0.1713 | 0.1801 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 69.70 | 770.96 | 1442 | 10312 | 0.1400 | 0.1805 |
| MCF 10A-H2B-mCherry | Neratinib | 0.56234 | 65.30 | 770.96 | 1416 | 9591 | 0.1476 | 0.1811 |
| MCF 10A-H2B-mCherry | Palbociclib | 10 | 58.60 | 770.96 | 1364 | 8264 | 0.1652 | 0.1815 |
| MCF 10A-H2B-mCherry | Palbociclib | 5.6234 | 63.00 | 770.96 | 1421 | 9152 | 0.1554 | 0.1830 |
| MCF 10A-H2B-mCherry | Palbociclib | 5.6234 | 67.50 | 770.96 | 1453 | 9939 | 0.1462 | 0.1837 |
| MCF 10A-H2B-mCherry | Palbociclib | 5.6234 | 78.60 | 770.96 | 1511 | 11443 | 0.1320 | 0.1848 |
| MCF 10A-H2B-mCherry | Palbociclib | 5.6234 | 65.30 | 770.96 | 1445 | 9591 | 0.1507 | 0.1848 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 67.50 | 770.96 | 1451 | 9939 | 0.1462 | 0.1849 |
| MCF 10A-H2B-mCherry | Palbociclib | 5.6234 | 56.40 | 770.96 | 1374 | 7845 | 0.1753 | 0.1854 |
| MCF 10A-H2B-mCherry | Palbociclib | 5.6234 | 74.10 | 770.96 | 1498 | 10921 | 0.1371 | 0.1855 |
| MCF 10A-H2B-mCherry | Palbociclib | 5.6234 | 71.90 | 770.96 | 1486 | 10631 | 0.1398 | 0.1855 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 36.40 | 770.96 | 1165 | 3985 | 0.2916 | 0.1855 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 65.30 | 770.96 | 1441 | 9591 | 0.1505 | 0.1859 |
| MCF 10A-H2B-mCherry | Palbociclib | 5.6234 | 69.70 | 770.96 | 1480 | 10312 | 0.1435 | 0.1861 |
| MCF 10A-H2B-mCherry | Palbociclib | 10 | 54.10 | 770.96 | 1347 | 7405 | 0.1822 | 0.1865 |
| MCF 10A-H2B-mCherry | Neratinib | 0.31623 | 51.90 | 770.96 | 1329 | 6944 | 0.1916 | 0.1865 |
| MCF 10A-H2B-mCherry | Neratinib | 0.56234 | 54.10 | 770.96 | 1349 | 7405 | 0.1826 | 0.1867 |
| MCF 10A-H2B-mCherry | Palbociclib | 5.6234 | 54.10 | 770.96 | 1356 | 7405 | 0.1833 | 0.1867 |
| MCF 10A-H2B-mCherry | Palbociclib | 5.6234 | 76.40 | 770.96 | 1513 | 11184 | 0.1353 | 0.1871 |
| MCF 10A-H2B-mCherry | Neratinib | 0.31623 | 40.80 | 770.96 | 1220 | 4874 | 0.2507 | 0.1873 |
| MCF 10A-H2B-mCherry | Palbociclib | 5.6234 | 60.80 | 770.96 | 1423 | 8711 | 0.1634 | 0.1877 |
| MCF 10A-H2B-mCherry | Palbociclib | 10 | 51.90 | 770.96 | 1332 | 6944 | 0.1920 | 0.1878 |