LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 4 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 1. - Dataset (ID:20312)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Taxol | 0.0018 | 9.60 | 770.96 | 1322 | 1178 | 1.1210 | 1.4079 |
| MCF 10A-H2B-mCherry | Etoposide | 0.1 | 2.90 | 770.96 | 894 | 886 | 1.0103 | 1.4136 |
| MCF 10A-H2B-mCherry | Palbociclib | 5.6234 | 2.90 | 770.96 | 887 | 886 | 1.0024 | 1.4153 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.0010833 | 5.10 | 770.96 | 1052 | 984 | 1.0683 | 1.4180 |
| MCF 10A-H2B-mCherry | Taxol | 0.0018 | 7.30 | 770.96 | 1169 | 1067 | 1.0942 | 1.4193 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.17783 | 2.90 | 770.96 | 907 | 886 | 1.0234 | 1.4253 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.31623 | 2.90 | 770.96 | 892 | 886 | 1.0090 | 1.4258 |
| MCF 10A-H2B-mCherry | Neratinib | 0.0013333 | 5.10 | 770.96 | 1033 | 984 | 1.0520 | 1.4280 |
| MCF 10A-H2B-mCherry | Taxol | 0.00013333 | 2.90 | 770.96 | 919 | 886 | 1.0363 | 1.4368 |
| MCF 10A-H2B-mCherry | Taxol | 0.0018 | 5.10 | 770.96 | 1058 | 984 | 1.0742 | 1.4442 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 7.30 | 770.96 | 1176 | 1067 | 1.1004 | 1.4520 |
| MCF 10A-H2B-mCherry | Etoposide | 0.17783 | 2.90 | 770.96 | 918 | 886 | 1.0366 | 1.4562 |
| MCF 10A-H2B-mCherry | Vorinostat | 10 | 2.90 | 770.96 | 915 | 886 | 1.0320 | 1.4790 |
| MCF 10A-H2B-mCherry | Alpelisib | 1 | 5.10 | 770.96 | 1058 | 984 | 1.0744 | 1.4794 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.56234 | 5.10 | 770.96 | 1052 | 984 | 1.0701 | 1.4873 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 2.90 | 770.96 | 925 | 886 | 1.0440 | 1.5079 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 5.10 | 770.96 | 1045 | 984 | 1.0639 | 1.5299 |
| MCF 10A-H2B-mCherry | Neratinib | 0.0033333 | 5.10 | 770.96 | 1047 | 984 | 1.0663 | 1.5331 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 2.90 | 770.96 | 910 | 886 | 1.0285 | 1.5401 |
| MCF 10A-H2B-mCherry | Neratinib | 0.31623 | 2.90 | 770.96 | 905 | 886 | 1.0232 | 1.5587 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 5.10 | 770.96 | 1074 | 984 | 1.0903 | 1.5622 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.031667 | 2.90 | 770.96 | 929 | 886 | 1.0479 | 1.5739 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 2.90 | 770.96 | 928 | 886 | 1.0477 | 1.5839 |
| MCF 10A-H2B-mCherry | Palbociclib | 10 | 5.10 | 770.96 | 1052 | 984 | 1.0712 | 1.5845 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.01 | 2.90 | 770.96 | 914 | 886 | 1.0328 | 1.5960 |