LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 4 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 1. - Dataset (ID:20312)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 9.60 | 770.96 | 1186 | 1178 | 1.0094 | 1.0594 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.01 | 18.60 | 770.96 | 1851 | 1786 | 1.0367 | 1.0606 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.0010833 | 31.90 | 770.96 | 3520 | 3294 | 1.0675 | 1.0616 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.01 | 25.30 | 770.96 | 2593 | 2456 | 1.0543 | 1.0617 |
| MCF 10A-H2B-mCherry | Alpelisib | 1 | 16.40 | 770.96 | 1680 | 1625 | 1.0338 | 1.0618 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.0033333 | 7.30 | 770.96 | 1072 | 1067 | 1.0042 | 1.0622 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.031667 | 16.40 | 770.96 | 1682 | 1625 | 1.0352 | 1.0642 |
| MCF 10A-H2B-mCherry | Neratinib | 0.0013333 | 23.00 | 770.96 | 2295 | 2193 | 1.0484 | 1.0645 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.01 | 23.00 | 770.96 | 2310 | 2193 | 1.0517 | 1.0649 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 25.30 | 770.96 | 2588 | 2456 | 1.0560 | 1.0655 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 9.60 | 770.96 | 1203 | 1178 | 1.0204 | 1.0657 |
| MCF 10A-H2B-mCherry | Etoposide | 0.056667 | 7.30 | 770.96 | 1072 | 1067 | 1.0061 | 1.0667 |
| MCF 10A-H2B-mCherry | Etoposide | 0.018333 | 18.60 | 770.96 | 1860 | 1786 | 1.0409 | 1.0667 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.0010833 | 27.50 | 770.96 | 2935 | 2754 | 1.0645 | 1.0672 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 65.30 | 770.96 | 10869 | 9591 | 1.1325 | 1.0685 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.0010833 | 29.70 | 770.96 | 3239 | 3022 | 1.0707 | 1.0687 |
| MCF 10A-H2B-mCherry | 0 | 2.90 | 770.96 | 881 | 886 | 0.9946 | 1.0689 | |
| MCF 10A-H2B-mCherry | Neratinib | 0.0013333 | 25.30 | 770.96 | 2594 | 2456 | 1.0579 | 1.0689 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.01 | 20.80 | 770.96 | 2057 | 1959 | 1.0488 | 1.0693 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.01 | 9.60 | 770.96 | 1198 | 1178 | 1.0181 | 1.0696 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 71.90 | 770.96 | 12125 | 10631 | 1.1400 | 1.0696 |
| MCF 10A-H2B-mCherry | Taxol | 0.001 | 7.30 | 770.96 | 1081 | 1067 | 1.0129 | 1.0696 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 7.30 | 770.96 | 1082 | 1067 | 1.0138 | 1.0699 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 69.70 | 770.96 | 11757 | 10312 | 1.1395 | 1.0700 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 74.10 | 770.96 | 12481 | 10921 | 1.1425 | 1.0701 |