LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 4 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 1. - Dataset (ID:20312)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 85.30 | 770.96 | 12073 | 12277 | 0.9833 | 0.9882 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.01 | 5.10 | 770.96 | 1018 | 984 | 1.0359 | 1.3108 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.01 | 7.30 | 770.96 | 1108 | 1067 | 1.0397 | 1.2001 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.01 | 11.90 | 770.96 | 1370 | 1319 | 1.0407 | 1.1198 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.01 | 14.10 | 770.96 | 1542 | 1478 | 1.0443 | 1.0978 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 2.90 | 770.96 | 912 | 886 | 1.0287 | 1.3736 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 5.10 | 770.96 | 1021 | 984 | 1.0370 | 1.2294 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 9.60 | 770.96 | 1203 | 1178 | 1.0204 | 1.0657 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 11.90 | 770.96 | 1339 | 1319 | 1.0140 | 1.0328 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 18.60 | 770.96 | 1818 | 1786 | 1.0159 | 1.0222 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 20.80 | 770.96 | 1975 | 1959 | 1.0071 | 1.0075 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 25.30 | 770.96 | 2462 | 2456 | 1.0009 | 0.9971 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 27.50 | 770.96 | 2756 | 2754 | 0.9993 | 0.9963 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 36.40 | 770.96 | 3957 | 3985 | 0.9917 | 0.9907 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 38.60 | 770.96 | 4381 | 4421 | 0.9897 | 0.9897 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 43.00 | 770.96 | 5338 | 5280 | 1.0103 | 1.0063 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 45.30 | 770.96 | 5695 | 5677 | 1.0027 | 1.0007 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 51.90 | 770.96 | 6948 | 6944 | 0.9999 | 0.9986 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 54.10 | 770.96 | 7425 | 7405 | 1.0018 | 0.9997 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 58.60 | 770.96 | 8381 | 8264 | 1.0132 | 1.0064 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 60.80 | 770.96 | 8875 | 8711 | 1.0180 | 1.0086 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 71.90 | 770.96 | 10621 | 10631 | 0.9985 | 0.9972 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 74.10 | 770.96 | 10929 | 10921 | 1.0003 | 0.9981 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.01 | 25.30 | 770.96 | 2543 | 2456 | 1.0369 | 1.0441 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.01 | 23.00 | 770.96 | 2267 | 2193 | 1.0356 | 1.0474 |