LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 4 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 1. - Dataset (ID:20312)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Dasatinib | 3.1623 | 78.60 | 770.96 | 1655 | 11443 | 0.1446 | 0.2158 |
| MCF 10A-H2B-mCherry | Alpelisib | 3.1623 | 7.30 | 770.96 | 1004 | 1067 | 0.9420 | 0.7976 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 45.30 | 770.96 | 1114 | 5677 | 0.1963 | 0.1358 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 47.50 | 770.96 | 1118 | 6082 | 0.1839 | 0.1325 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 63.00 | 770.96 | 985 | 9152 | 0.1076 | 0.0682 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 87.50 | 770.96 | 862 | 12567 | 0.0687 | -0.0162 |
| MCF 10A-H2B-mCherry | Palbociclib | 3.1623 | 47.50 | 770.96 | 1461 | 6082 | 0.2398 | 0.2366 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 34.10 | 770.96 | 1213 | 3605 | 0.3364 | 0.2251 |
| MCF 10A-H2B-mCherry | Dasatinib | 3.1623 | 69.70 | 770.96 | 1628 | 10312 | 0.1579 | 0.2207 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 36.40 | 770.96 | 1208 | 3985 | 0.3030 | 0.2078 |
| MCF 10A-H2B-mCherry | Dasatinib | 3.1623 | 67.50 | 770.96 | 1622 | 9939 | 0.1632 | 0.2229 |
| MCF 10A-H2B-mCherry | Dasatinib | 3.1623 | 71.90 | 770.96 | 1636 | 10631 | 0.1539 | 0.2194 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 31.90 | 770.96 | 1231 | 3294 | 0.3737 | 0.2497 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 38.60 | 770.96 | 1214 | 4421 | 0.2744 | 0.1966 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 25.30 | 770.96 | 1259 | 2456 | 0.5128 | 0.3407 |
| MCF 10A-H2B-mCherry | Dasatinib | 3.1623 | 63.00 | 770.96 | 1594 | 9152 | 0.1742 | 0.2253 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 27.50 | 770.96 | 1270 | 2754 | 0.4611 | 0.3114 |
| MCF 10A-H2B-mCherry | Dasatinib | 3.1623 | 60.80 | 770.96 | 1568 | 8711 | 0.1801 | 0.2246 |
| MCF 10A-H2B-mCherry | Dasatinib | 3.1623 | 74.10 | 770.96 | 1635 | 10921 | 0.1498 | 0.2164 |
| MCF 10A-H2B-mCherry | Dasatinib | 3.1623 | 65.30 | 770.96 | 1600 | 9591 | 0.1668 | 0.2219 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 23.00 | 770.96 | 1250 | 2193 | 0.5701 | 0.3769 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 29.70 | 770.96 | 1195 | 3022 | 0.3953 | 0.2482 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 40.80 | 770.96 | 1135 | 4874 | 0.2330 | 0.1557 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 14.10 | 770.96 | 1181 | 1478 | 0.7988 | 0.5740 |
| MCF 10A-H2B-mCherry | Dasatinib | 3.1623 | 54.10 | 770.96 | 1522 | 7405 | 0.2056 | 0.2311 |