LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 4 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 1. - Dataset (ID:20312)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 29.70 | 770.96 | 3416 | 3022 | 1.1281 | 1.1224 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 43.00 | 770.96 | 5963 | 5280 | 1.1278 | 1.0866 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 49.70 | 770.96 | 7346 | 6511 | 1.1272 | 1.0777 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 31.90 | 770.96 | 3716 | 3294 | 1.1258 | 1.1129 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 25.30 | 770.96 | 2763 | 2456 | 1.1232 | 1.1403 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 40.80 | 770.96 | 5481 | 4874 | 1.1225 | 1.0863 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 27.50 | 770.96 | 3095 | 2754 | 1.1217 | 1.1250 |
| MCF 10A-H2B-mCherry | Taxol | 0.0018 | 9.60 | 770.96 | 1322 | 1178 | 1.1210 | 1.4079 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 45.30 | 770.96 | 6360 | 5677 | 1.1186 | 1.0773 |
| MCF 10A-H2B-mCherry | Neratinib | 0.56234 | 5.10 | 770.96 | 1099 | 984 | 1.1184 | 1.8513 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 20.80 | 770.96 | 2183 | 1959 | 1.1127 | 1.1610 |
| MCF 10A-H2B-mCherry | Taxol | 0.0018 | 18.60 | 770.96 | 1987 | 1786 | 1.1116 | 1.1804 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 14.10 | 770.96 | 1644 | 1478 | 1.1110 | 1.2335 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 18.60 | 770.96 | 1984 | 1786 | 1.1089 | 1.1742 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 11.90 | 770.96 | 1462 | 1319 | 1.1065 | 1.2720 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 16.40 | 770.96 | 1799 | 1625 | 1.1054 | 1.1892 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 23.00 | 770.96 | 2426 | 2193 | 1.1049 | 1.1329 |
| MCF 10A-H2B-mCherry | Taxol | 0.0056234 | 16.40 | 770.96 | 1788 | 1625 | 1.1007 | 1.1856 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 7.30 | 770.96 | 1176 | 1067 | 1.1004 | 1.4520 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 9.60 | 770.96 | 1294 | 1178 | 1.0969 | 1.3188 |
| MCF 10A-H2B-mCherry | Taxol | 0.0056234 | 14.10 | 770.96 | 1618 | 1478 | 1.0947 | 1.2026 |
| MCF 10A-H2B-mCherry | Taxol | 0.0018 | 7.30 | 770.96 | 1169 | 1067 | 1.0942 | 1.4193 |
| MCF 10A-H2B-mCherry | Taxol | 0.0018 | 20.80 | 770.96 | 2141 | 1959 | 1.0917 | 1.1323 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.0010833 | 16.40 | 770.96 | 1773 | 1625 | 1.0904 | 1.1647 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 5.10 | 770.96 | 1074 | 984 | 1.0903 | 1.5622 |