LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 4 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 1. - Dataset (ID:20312)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 67.50 | 770.96 | 10383 | 9939 | 1.0452 | 1.0228 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 85.30 | 770.96 | 12831 | 12277 | 1.0451 | 1.0198 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.01 | 36.40 | 770.96 | 4157 | 3985 | 1.0448 | 1.0369 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.01 | 47.50 | 770.96 | 6344 | 6082 | 1.0446 | 1.0291 |
| MCF 10A-H2B-mCherry | Neratinib | 0.0053333 | 83.10 | 770.96 | 12537 | 12002 | 1.0445 | 1.0221 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.0033333 | 83.10 | 770.96 | 12536 | 12002 | 1.0444 | 1.0219 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.01 | 14.10 | 770.96 | 1542 | 1478 | 1.0443 | 1.0978 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 2.90 | 770.96 | 925 | 886 | 1.0440 | 1.5079 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.0010833 | 67.50 | 770.96 | 10380 | 9939 | 1.0438 | 1.0215 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 27.50 | 770.96 | 2865 | 2754 | 1.0432 | 1.0456 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.01 | 27.50 | 770.96 | 2866 | 2754 | 1.0426 | 1.0462 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 74.10 | 770.96 | 11386 | 10921 | 1.0426 | 1.0205 |
| MCF 10A-H2B-mCherry | Neratinib | 0.0033333 | 27.50 | 770.96 | 2866 | 2754 | 1.0425 | 1.0458 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.01 | 43.00 | 770.96 | 5494 | 5280 | 1.0421 | 1.0295 |
| MCF 10A-H2B-mCherry | Neratinib | 0.0013333 | 54.10 | 770.96 | 7702 | 7405 | 1.0420 | 1.0237 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 69.70 | 770.96 | 10742 | 10312 | 1.0419 | 1.0207 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 9.60 | 770.96 | 1227 | 1178 | 1.0416 | 1.1417 |
| MCF 10A-H2B-mCherry | Neratinib | 0.0013333 | 40.80 | 770.96 | 5064 | 4874 | 1.0415 | 1.0298 |
| MCF 10A-H2B-mCherry | Neratinib | 0.0013333 | 18.60 | 770.96 | 1857 | 1786 | 1.0414 | 1.0715 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.56234 | 14.10 | 770.96 | 1538 | 1478 | 1.0411 | 1.0908 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 71.90 | 770.96 | 11066 | 10631 | 1.0410 | 1.0198 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.01 | 16.40 | 770.96 | 1690 | 1625 | 1.0410 | 1.0775 |
| MCF 10A-H2B-mCherry | Etoposide | 0.018333 | 18.60 | 770.96 | 1860 | 1786 | 1.0409 | 1.0667 |
| MCF 10A-H2B-mCherry | Etoposide | 0.018333 | 14.10 | 770.96 | 1539 | 1478 | 1.0408 | 1.0865 |
| MCF 10A-H2B-mCherry | Neratinib | 0.0013333 | 47.50 | 770.96 | 6318 | 6082 | 1.0408 | 1.0258 |