LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 4 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 1. - Dataset (ID:20312)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Neratinib | 0.56234 | 2.90 | 770.96 | 1019 | 886 | 1.1516 | 3.5501 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 2.90 | 770.96 | 943 | 886 | 1.0662 | 2.3433 |
| MCF 10A-H2B-mCherry | Palbociclib | 10 | 2.90 | 770.96 | 953 | 886 | 1.0766 | 2.3291 |
| MCF 10A-H2B-mCherry | Neratinib | 0.0033333 | 2.90 | 770.96 | 939 | 886 | 1.0622 | 2.2869 |
| MCF 10A-H2B-mCherry | Alpelisib | 5.6234 | 2.90 | 770.96 | 919 | 886 | 1.0389 | 2.2662 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 2.90 | 770.96 | 934 | 886 | 1.0555 | 2.2053 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.56234 | 2.90 | 770.96 | 950 | 886 | 1.0739 | 2.1723 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 2.90 | 770.96 | 964 | 886 | 1.0866 | 2.1195 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 2.90 | 770.96 | 951 | 886 | 1.0723 | 1.9578 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.56234 | 2.90 | 770.96 | 928 | 886 | 1.0486 | 1.9019 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.0010833 | 2.90 | 770.96 | 951 | 886 | 1.0731 | 1.8915 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.01 | 2.90 | 770.96 | 932 | 886 | 1.0524 | 1.8753 |
| MCF 10A-H2B-mCherry | Neratinib | 0.0013333 | 2.90 | 770.96 | 920 | 886 | 1.0407 | 1.8637 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 2.90 | 770.96 | 950 | 886 | 1.0720 | 1.8576 |
| MCF 10A-H2B-mCherry | Neratinib | 0.56234 | 5.10 | 770.96 | 1099 | 984 | 1.1184 | 1.8513 |
| MCF 10A-H2B-mCherry | Alpelisib | 1 | 2.90 | 770.96 | 941 | 886 | 1.0614 | 1.8391 |
| MCF 10A-H2B-mCherry | Taxol | 0.0018 | 2.90 | 770.96 | 947 | 886 | 1.0682 | 1.8211 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.31623 | 2.90 | 770.96 | 886 | 886 | 1.0012 | 1.8207 |
| MCF 10A-H2B-mCherry | Neratinib | 0.17783 | 2.90 | 770.96 | 919 | 886 | 1.0386 | 1.7712 |
| MCF 10A-H2B-mCherry | Etoposide | 0.018333 | 2.90 | 770.96 | 945 | 886 | 1.0660 | 1.7645 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.031667 | 2.90 | 770.96 | 939 | 886 | 1.0600 | 1.7584 |
| MCF 10A-H2B-mCherry | Neratinib | 0.056234 | 2.90 | 770.96 | 902 | 886 | 1.0202 | 1.6271 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 5.10 | 770.96 | 1051 | 984 | 1.0711 | 1.6265 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.01 | 2.90 | 770.96 | 914 | 886 | 1.0328 | 1.5960 |
| MCF 10A-H2B-mCherry | Palbociclib | 10 | 5.10 | 770.96 | 1052 | 984 | 1.0712 | 1.5845 |